(Q42635431)

English

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

scientific article published on January 1998

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility (English)

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

author name string

Fincham VJ

1

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Frame MC

2

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

language of work or name

0 references

publication date

1 January 1998

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

17

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

1

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

81-92

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

SH2 and SH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Signalling through SH2 and SH3 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Actin dynamics in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

pp60(c-src) is required for cell locomotion regulated by the hyaluronanreceptor RHAMM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Cell migration: a physically integrated molecular process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Excess early signaling activity inhibits cellular chemotaxis toward PDGF-BB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Separation of v-Src-induced mitogenesis and morphological transformation by inhibition of AP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Protein tyrosine kinases, with emphasis on the Src family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Size-Variant pp60src Proteins of Recovered Avian Sarcoma Viruses Interact with Adhesion Plaques as Peripheral Membrane Proteins: Effects on Cell Transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

A single point mutation has pleiotropic effects on pp60v-src function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Structural differences between repressed and derepressed forms of p60c-src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Transmembrane molecular assemblies in cell-extracellular matrix interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Association of p60c-src with endosomal membranes in mammalian fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Differential expression of Rous Sarcoma virus-specific transformation parameters in enucleated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170360

27 May 2018

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/9427743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9427743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9427743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/17.1.81

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

ResearchGate publication ID

0 references

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