(Q42667685)

English

Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis

scientific article published on 21 February 2006

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scholarly article

1 reference

Europe PubMed Central

4 November 2017

Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis (English)

1 reference

Europe PubMed Central

4 November 2017

liver cirrhosis

0 references

3

1 reference

Europe PubMed Central

4 November 2017

author name string

Q Zhou

1

1 reference

Europe PubMed Central

4 November 2017

M Hennenberg

2

1 reference

Europe PubMed Central

4 November 2017

K Jochem

4

1 reference

Europe PubMed Central

4 November 2017

L Leifeld

5

1 reference

Europe PubMed Central

4 November 2017

E Biecker

6

1 reference

Europe PubMed Central

4 November 2017

T Sauerbruch

7

1 reference

Europe PubMed Central

4 November 2017

J Heller

8

1 reference

Europe PubMed Central

4 November 2017

language of work or name

0 references

publication date

21 February 2006

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

55

1 reference

Europe PubMed Central

4 November 2017

9

1 reference

Europe PubMed Central

4 November 2017

1296-1305

1 reference

Europe PubMed Central

4 November 2017

Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Increased hepatic resistance: a new target in the pharmacologic therapy of portal hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Portal hypertension: from bedside to bench.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Rocks: multifunctional kinases in cell behaviour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Rho GTPases in cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Hepatic blood flow regulation by stellate cells in normal and injured liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Cellular and molecular basis of portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Regional and systemic hemodynamic disturbances in cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Characterisation of portal hypertension models by microspheres in anaesthetised rats: a comparison of liver flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Rho GTPases and their effector proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Activation of moesin and adducin by Rho-kinase downstream of Rho.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Role of Rho small GTP binding protein in the regulation of actin cytoskeleton in hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Pharmacomechanical coupling: the role of calcium, G-proteins, kinases and phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin, and nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Anesthetic influences on regional hemodynamics in normal and hemorrhaged rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Portal venous pressure and portasystemic shunting in experimental portal hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Enhanced vasoconstrictor response of the isolated perfused cirrhotic rat liver to humoral vasoconstrictor substances found in portal venous blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

27 May 2018

Acute haemodynamic effects of losartan in anaesthetized cirrhotic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

5-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Rho activation in excitatory agonist-stimulated vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1860046

16 August 2018

Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of organ blood flow with coloured microspheres in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-induced vasoconstriction in isolated perfused liver preparations from normal and cirrhotic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed endothelin receptor antagonist, SB209670, decreases portal pressure in biliary cirrhotic rats in vivo by reducing portal venous system resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid enhances collagen gel contraction by hepatic stellate cells: association with rho-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid-induced platelet shape change proceeds via Rho/Rho kinase-mediated myosin light-chain and moesin phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepatic endothelin-1 levels and endothelin receptor density in cirrhotic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROCK inhibitor Y-27632 attenuates stellate cell contraction and portal pressure increase induced by endothelin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16492715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1136/GUT.2005.081059

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

1 reference

Europe PubMed Central

4 November 2017

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