(Q42672180)

English

The membrane topography of the diphtheria toxin T domain linked to the a chain reveals a transient transmembrane hairpin and potential translocation mechanisms

scientific article published on November 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

The membrane topography of the diphtheria toxin T domain linked to the a chain reveals a transient transmembrane hairpin and potential translocation mechanisms (English)

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

transmembrane protein

0 references

author name string

Jie Wang

1

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Erwin London

2

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

language of work or name

0 references

publication date

1 November 2009

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

48

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

43

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

10446-10456

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

Kinetic intermediate reveals staggered pH-dependent transitions along the membrane insertion pathway of the diphtheria toxin T-domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Structure of a complex of the ATPase SecA and the protein-translocation channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

An amino acid "transmembrane tendency" scale that approaches the theoretical limit to accuracy for prediction of transmembrane helices: relationship to biological hydrophobicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Topography of the hydrophilic helices of membrane-inserted diphtheria toxin T domain: TH1-TH3 as a hydrophilic tether

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Topography of diphtheria toxin A chain inserted into lipid vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

X-ray structure of a protein-conducting channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Topography of diphtheria Toxin's T domain in the open channel state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Cell surface monkey CD9 antigen is a coreceptor that increases diphtheria toxin sensitivity and diphtheria toxin receptor affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

The N-terminal alpha-helix of fragment B of diphtheria toxin promotes translocation of fragment A into the cytoplasm of eukaryotic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Diphtheria toxin and related proteins. 3. Reconstitution of hybrid "diphtheria toxin" from nontoxic mutant proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

pH-dependence of the phospholipid interaction of diphtheria-toxin fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

The crystal structure of diphtheria toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Diphtheria toxin: membrane interaction and membrane translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

Diphtheria Toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

27 May 2018

A role for the two-helix finger of the SecA ATPase in protein translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin T domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Behavior of diphtheria toxin T domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Analyzing topography of membrane-inserted diphtheria toxin T domain using BODIPY-streptavidin: at low pH, helices 8 and 9 form a transmembrane hairpin but helices 5-7 form stable nonclassical inserted segments on the cis side of the bilayer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Characterization of diphtheria toxin's catalytic domain interaction with lipid membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Topography of helices 5-7 in membrane-inserted diphtheria toxin T domain: identification and insertion boundaries of two hydrophobic sequences that do not form a stable transmembrane hairpin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

The effects of inhibitors upon pore formation by diphtheria toxin and diphtheria toxin T domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Reconstitution of diphtheria toxin from two nontoxic cross-reacting mutant proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

16 August 2018

Membrane Translocation of Charged Residues at the Tips of Hydrophobic Helices in the T Domain of Diphtheria Toxin†

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783497

1 December 2018

Structure-Activity Relationships in Diphtheria Toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diphtheria Toxin: Specific Competition for Cell Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation and model membrane interactions of diphtheria toxin fragment A

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 4 receptor targeted cytotoxicity: Genetic construction andin vivo immunosuppressive activity of a diphtheria toxin-related murine interleukin 4 fusion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships in diphtheria toxin channels: III. Residues which affect the cis pH dependence of channel conductance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic transitions of the transmembrane domain of diphtheria toxin: disulfide trapping and fluorescence proximity studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical Analysis Shows All Three Domains of Diphtheria Toxin Penetrate across Model Membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane Topography of the T Domain of Diphtheria Toxin Probed with Single Tryptophan Mutants†

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Diphtheria Toxin T Domain with Molten Globule-Like Proteins and Its Implications for Translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The diphtheria toxin channel-forming T-domain translocates its own NH2-terminal region and the catalytic domain across planar phospholipid bilayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the Membrane-Inserted Diphtheria Toxin T Domain with Peptides and Its Possible Implications for Chaperone-like T Domain Behavior†

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavior of the deeply inserted helices in diphtheria toxin T domain: helices 5, 8, and 9 interact strongly and promote pore formation, while helices 6/7 limit pore formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19780588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI9014665

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

release_7demh37tknbp3oi6rcoogsctxu

1 reference

https://api.fatcat.wiki/v0/release/7demh37tknbp3oi6rcoogsctxu

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 November 2017

PubMed publication ID

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Europe PubMed Central

PMC publication ID

4 November 2017

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