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Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.
scientific article published on December 2000
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
spliceosome
0 references
author
Ren-Jang Lin
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
S L Yean
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
G Wuenschell
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
J Termini
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
language of work or name
English
0 references
publication date
1 December 2000
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Nature
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
408
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
6814
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
881-884
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
The question remains: is the spliceosome a ribozyme?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
A tertiary interaction that links active-site domains to the 5' splice site of a group II intron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Phosphorothioate substitution can substantially alter RNA conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Does a single metal ion bridge the A-9 and scissile phosphate groups in the catalytically active hammerhead ribozyme structure?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Mechanical devices of the spliceosome: motors, clocks, springs, and things
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
A second catalytic metal ion in a group I ribozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5' splice site.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
The spliceosome is a dynamic ribonucleoprotein machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Metal ion catalysis in the Tetrahymena ribozyme reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
A general two-metal-ion mechanism for catalytic RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Ribozymes: A Distinct Class of Metalloenzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Split genes and RNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
U6 snRNA function in nuclear pre-mRNA splicing: a phosphorothioate interference analysis of the U6 phosphate backbone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicingin vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
27 May 2018
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
16 August 2018
Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
16 August 2018
Metal ion catalysis during splicing of premessenger RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090
retrieved
1 December 2018
Catalytic site components common to both splicing steps of a group II intron
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11130730
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/35048617
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Dimensions Publication ID
1013079623
0 references
PMC publication ID
4377090
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
11130730
1 reference
stated in
Europe PubMed Central
PMC publication ID
4377090
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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