(Q42699528)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

The role of germline promoters and I exons in cytokine-induced gene-specific class switch recombination (English)

1 reference

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17 January 2020

3

1 reference

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17 January 2020

author name string

Wesley A Dunnick

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jian Shi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Clinton Fontaine

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

John T Collins

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

3 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Journal of Immunology

1 reference

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17 January 2020

volume

186

1 reference

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17 January 2020

issue

1

1 reference

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17 January 2020

page(s)

350-358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes.

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Switch region identity plays an important role in Ig class switch recombination

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Molecular processes that regulate class switching

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Processing of switch transcripts is required for targeting of antibody class switch recombination

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Shutdown of class switch recombination by deletion of a switch region control element.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Germline transcripts of the murine immunoglobulin gamma 2a gene: structure and induction by IFN-gamma

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Expression of I mu-C gamma hybrid germline transcripts subsequent to immunoglobulin heavy chain class switching

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s)

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Regulation of Ig Class Secretion by Soluble Products of Certain T-Cell Lines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Double isotype production by a neoplastic B cell line. II. Allelically excluded production of mu and gamma 1 heavy chains without CH gene rearrangement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Structure of Germline Immunoglobulin Heavy-Chainγ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059604

Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production

16 August 2018

1 reference

12 December 2020

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination

1 reference

12 December 2020

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

1 reference

12 December 2020

Switch transcripts in immunoglobulin class switching

1 reference

12 December 2020

Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals

1 reference

12 December 2020

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice

1 reference

12 December 2020

Integrating signals from IFN-gamma and IL-4 by B cells: positive and negative effects on CD40 ligand-induced proliferation, survival, and division-linked isotype switching to IgG1, IgE, and IgG2a

1 reference

12 December 2020

Induced expression of murine gamma2a by CD40 ligation independently of IFN-gamma

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1003108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21131417%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21131417

1 reference