(Q42705294)

English

Effects of a partial agonist and a full antagonist acting at the glycine site of the NMDA receptor on inflammation-induced mechanical hyperalgesia in rats

scientific article published on April 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Effects of a partial agonist and a full antagonist acting at the glycine site of the NMDA receptor on inflammation-induced mechanical hyperalgesia in rats (English)

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

author name string

Laird JM

1

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Mason GS

2

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Webb J

3

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Hill RG

4

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Hargreaves RJ

5

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

language of work or name

0 references

publication date

1 April 1996

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Europe PubMed Central

PMC publication ID

5 November 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

117

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

7

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

1487-1492

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

The Effects of NMDA Antagonists on Neuronal Activity in Cat Spinal Cord Evoked by Acute Inflammation in the Knee Joint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The contribution of NMDA receptor activation to spinal c-Fos expression in a model of inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The glycine site of the NMDA receptor--five years on.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966), an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Response of chronic neuropathic pain syndromes to ketamine: a preliminary study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Competitive as well as uncompetitive N-methyl-D-aspartate receptor antagonists affect cortical neuronal morphology and cerebral glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The effect of N-methyl-D-aspartate antagonist (ketamine) on single and repeated nociceptive stimuli: a placebo-controlled experimental human study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Ketamine as an adjunct to morphine in the treatment of pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Ketamine--its pharmacology and therapeutic uses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The effects of electrical stimulation of A and C visceral afferent fibres on the excitability of viscerosomatic neurones in the thoracic spinal cord of the cat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

A cure for wind up: NMDA receptor antagonists as potential analgesics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Sites for Antagonism on the N-Methyl-D-Aspartate Receptor Channel Complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

R-(+)-HA-966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Activity-dependent neuronal plasticity following tissue injury and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

27 May 2018

Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

Ketamine hydrochloride in the treatment of phantom limb pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909461

16 August 2018

Age-related change in the proportion of amyloid precursor protein mRNAs in the gray matter of cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of morphine, MK-801, an NMDA antagonist, and CP-96,345, an NK1 antagonist, on the hyperesthesia evoked by carageenan injection in the rat paw

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced responses of rat dorsal horn neurones after UV irradiation of the hindpaw; roles of the NMDA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of the clinically tested NMDA receptor antagonist memantine on carrageenan-induced thermal hyperalgesia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcutaneous carrageenan, but not formalin, increases the excitability of the nociceptive flexor reflex in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The behavioural effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(+)-HA 966, a partial agonist at the glycine site coupled to NMDA receptors, blocks formalin-induced pain in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinically tested N-methyl-D-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitability changes of somatic and viscero-somatic nociceptive reflexes in the decerebrate-spinal rabbit: role of NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8730744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1996.TB15311.X

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

ResearchGate publication ID

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