(Q42709692)

English

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

scientific article published on February 1996

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scholarly article

1 reference

Europe PubMed Central

5 November 2017

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors (English)

1 reference

Europe PubMed Central

5 November 2017

Trypanosoma cruzi

0 references

author name string

Serveau C

1

1 reference

Europe PubMed Central

5 November 2017

Lalmanach G

2

1 reference

Europe PubMed Central

5 November 2017

Juliano MA

3

1 reference

Europe PubMed Central

5 November 2017

Scharfstein J

4

1 reference

Europe PubMed Central

5 November 2017

Juliano L

5

1 reference

Europe PubMed Central

5 November 2017

Gauthier F

6

1 reference

Europe PubMed Central

5 November 2017

language of work or name

0 references

publication date

1 February 1996

1 reference

Europe PubMed Central

5 November 2017

Biochemical Journal

1 reference

Europe PubMed Central

5 November 2017

313 ( Pt 3)

1 reference

Europe PubMed Central

5 November 2017

951-956

1 reference

Europe PubMed Central

5 November 2017

Cysteine proteinases of parasitic protozoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Two distinct gene subfamilies within the family of cysteine protease genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The proteases and pathogenicity of parasitic protozoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Differential changes in the association and dissociation rate constants for binding of cystatins to target proteinases occurring on N-terminal truncation of the inhibitors indicate that the interaction mechanism varies with different enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Cathepsin B, Cathepsin H, and cathepsin L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Cystatin, a protein inhibitor of cysteine proteinases. Improved purification from egg white, characterization, and detection in chicken serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Cysteine-proteinase-inhibiting function of T kininogen and of its proteolytic fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual C-terminal extension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The C-terminal extension of the major cysteine proteinase (cruzipain) from Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Self-proteolysis of the cysteine proteinase, cruzipain, from Trypanosoma cruzi gives a major fragment corresponding to its carboxy-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Hydrosoluble fluorogenic substrates for plasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Inhibitors of the major cysteinyl proteinase (GP57/51) impair host cell invasion and arrest the intracellular development of Trypanosoma cruzi in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Intramolecularly quenched fluorogenic peptide substrates for human renin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Recombinant chicken egg white cystatin variants of the QLVSG region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Intramolecularly quenched fluorogenic tetrapeptide substrates for tissue and plasma kallikreins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

27 May 2018

Analysis of mRNAs that Accumulate in Response to Low Temperature Identifies a Thiol Protease Gene in Tomato

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

16 August 2018

Identification of new cysteine protease gene isoforms in Trypanosoma cruzi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

16 August 2018

The crystal structure of cruzain: a therapeutic target for Chagas' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

16 August 2018

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

16 August 2018

Trypanosoma cruzi: characterization and isolation of a 57/51,000 m.w. surface glycoprotein (GP57/51) expressed by epimastigotes and bloodstream trypomastigotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217003

1 December 2018

Further characterization and partial amino acid sequence of a cysteine proteinase from Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine proteinase in Trypanosoma cruzi: immunocytochemical localization and involvement in parasite-host cell interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and expression of proteases during Trypanosoma cruzi metacyclogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional identification of GP57/51 antigen of Trypanosoma cruzi as a cysteine proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystatin C based peptidyl diazomethanes as cysteine proteinase inhibitors: influence of the peptidyl chain length

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Papain-inhibitory activity of oryzacystatin, a rice seed cysteine proteinase inhibitor, depends on the central Gln-Val-Val-Ala-Gly region conserved among cystatin superfamily members

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alignment/phylogeny of the papain superfamily of cysteine proteases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide derivatives specific for a Plasmodium falciparum proteinase inhibit the human erythrocyte invasion by merozoites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major cysteine proteinase is developmentally regulated in Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The specificity of the S1' subsite of cysteine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new, sensitive fluorogenic substrate for papain based on the sequence of the cystatin inhibitory site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature-dependent substrate inhibition of the cysteine proteinase (GP57/51) from Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between cystatin-derived peptides and papain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8611180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3130951

1 reference

Europe PubMed Central

5 November 2017

1 reference

Europe PubMed Central

5 November 2017

1 reference

Europe PubMed Central

5 November 2017

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0 references

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