(Q42715690)

English

Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Layton H. Smith

22

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Anthony B Pinkerton

23

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Patrick R Maloney

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Pasha Khan

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Michael Hedrick

3

1 reference

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9 March 2020

Palak Gosalia

4

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9 March 2020

Monika Milewski

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Linda Li

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Gregory P Roth

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Eduard Sergienko

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Eigo Suyama

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Eliot Sugarman

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Kevin Nguyen

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Alka Mehta

12

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9 March 2020

Stefan Vasile

13

1 reference

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9 March 2020

Ying Su

14

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Derek Stonich

15

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Hung Nguyen

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Fu-Yue Zeng

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Arianna Mangravita Novo

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Michael Vicchiarelli

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Jena Diwan

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Thomas D Y Chung

21

1 reference

Europe PubMed Central

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9 March 2020

language of work or name

0 references

publication date

7 September 2012

1 reference

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9 March 2020

number of pages

5

1 reference

based on heuristic

inferred from page(s)

Bioorganic & Medicinal Chemistry Letters

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

22

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

6656-6660

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin is necessary for the maintenance of insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Abnormal fluid homeostasis in apelin receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Family-based analysis of apelin and AGTRL1 gene polymorphisms with hypertension in Han Chinese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin stimulates glucose utilization in normal and obese insulin-resistant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Involvement of a Stat3 binding site in inflammation-induced enteric apelin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

A possible role for hypoxia-induced apelin expression in enteric cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin, a newly identified adipokine up-regulated by insulin and obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Apelin, a new enteric peptide: localization in the gastrointestinal tract, ontogeny, and stimulation of gastric cell proliferation and of cholecystokinin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Inhibitory effect of apelin-12 on nocturnal food intake in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Characterization of apelin, the ligand for the APJ receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

27 May 2018

Elevated plasma levels of apelin in children with type 1 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

16 August 2018

Effects of rosiglitazone and metformin treatment on apelin, visfatin, and ghrelin levels in patients with type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

16 August 2018

Low plasma apelin levels in newly diagnosed type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

16 August 2018

Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729231

16 August 2018

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apelin cells in the rat stomach

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased colonic apelin production in rodents with experimental colitis and in humans with IBD

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apelin activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23010269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMCL.2012.08.105

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010269%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

ResearchGate publication ID

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