(Q42726265)

5 November 2017

MegaTevs: single-chain dual nucleases for efficient gene disruption (English)

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5 November 2017

Jason M Wolfs

1

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5 November 2017

Matthew DaSilva

2

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5 November 2017

Sarah E Meister

3

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5 November 2017

Xu Wang

4

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5 November 2017

Caroline Schild-Poulter

5

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5 November 2017

David R Edgell

6

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5 November 2017

language of work or name

English

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publication date

10 July 2014

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5 November 2017

Nucleic Acids Research

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5 November 2017

42

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5 November 2017

13

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5 November 2017

8816-8829

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Creative Commons Attribution 3.0 Unported

5 November 2017

start time

4 October 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4117789/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Genome engineering with TAL-effector nucleases and alternative modular nuclease technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

FokI dimerization is required for DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 January 2018

1 reference

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An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 January 2018

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Technology: a CRISPR genome-editing tool

21 January 2018

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21 January 2018

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

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Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells

21 January 2018

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Synthesis of programmable integrases

21 January 2018

1 reference

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Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases.

21 January 2018

1 reference

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TALE-PvuII fusion proteins--novel tools for gene targeting.

21 January 2018

1 reference

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Monomeric site-specific nucleases for genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Compact designer TALENs for efficient genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

21 January 2018

1 reference

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Regulation of DNA double-strand break repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption

21 January 2018

1 reference

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High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes

21 January 2018

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Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

21 January 2018

1 reference

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

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Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

A unified genetic, computational and experimental framework identifies functionally relevant residues of the homing endonuclease I-BmoI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

High-frequency modification of plant genes using engineered zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Rapid screening of endonuclease target site preference using a modified bacterial two-plasmid selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Tapping natural reservoirs of homing endonucleases for targeted gene modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Coincidence of cleavage sites of intron endonuclease I-TevI and critical sequences of the host thymidylate synthase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Intron mobility in phage T4 is dependent upon a distinctive class of endonucleases and independent of DNA sequences encoding the intron core: mechanistic and evolutionary implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Homing endonuclease structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Exon coconversion biases accompanying intron homing: battle of the nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Regulation of endonuclease activity in human nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Exploitation of binding energy for catalysis and design

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Redesign of extensive protein-DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Distribution, sequence homology, and homing of group I introns among T-even-like bacteriophages: evidence for recent transfer of old introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

Site-specific cleavage of DNA–RNA hybrids by zinc finger/FokI cleavage domain fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKU573

21 January 2018

Identifiers

DOI

10.1093/NAR/GKU573

1 reference

5 November 2017

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5 November 2017

PubMed publication ID

25013171

1 reference