(Q42728391)

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Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat.

scientific article published on 2 August 2011

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1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

author name string

Mark R Fielden

1

1 reference

Europe PubMed Central

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5 November 2017

Alex Adai

2

1 reference

Europe PubMed Central

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5 November 2017

Robert T Dunn

3

1 reference

Europe PubMed Central

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5 November 2017

Andrew Olaharski

4

1 reference

Europe PubMed Central

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5 November 2017

George Searfoss

5

1 reference

Europe PubMed Central

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5 November 2017

Joe Sina

6

1 reference

Europe PubMed Central

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5 November 2017

Jiri Aubrecht

7

1 reference

Europe PubMed Central

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5 November 2017

Eric Boitier

8

1 reference

Europe PubMed Central

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5 November 2017

Paul Nioi

9

1 reference

Europe PubMed Central

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5 November 2017

Scott Auerbach

10

1 reference

Europe PubMed Central

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5 November 2017

David Jacobson-Kram

11

1 reference

Europe PubMed Central

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5 November 2017

Nandini Raghavan

12

1 reference

Europe PubMed Central

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5 November 2017

Yi Yang

13

1 reference

Europe PubMed Central

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5 November 2017

Andrew Kincaid

14

1 reference

Europe PubMed Central

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5 November 2017

Jon Sherlock

15

1 reference

Europe PubMed Central

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5 November 2017

Shen-Jue Chen

16

1 reference

Europe PubMed Central

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5 November 2017

Bruce Car

17

1 reference

Europe PubMed Central

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5 November 2017

Predictive Safety Testing Consortium, Carcinogenicity Working Group

18

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Europe PubMed Central

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5 November 2017

publication date

2 August 2011

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5 November 2017

Toxicological Sciences

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5 November 2017

124

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5 November 2017

1

1 reference

Europe PubMed Central

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5 November 2017

54-74

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

Prediction of rodent carcinogenesis: an evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies

1 reference

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21 January 2018

Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning

1 reference

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21 January 2018

Toxicogenomics and cancer risk assessment: a framework for key event analysis and dose-response assessment for nongenotoxic carcinogens

1 reference

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21 January 2018

Review of the in vitro and in vivo genotoxicity of dichlorvos

1 reference

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21 January 2018

Update on genotoxicity and carcinogenicity testing of 472 marketed pharmaceuticals

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21 January 2018

Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1.

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

European Experience in Chemicals Management: Integrating Science into Policy

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21 January 2018

Human carcinogenic risk evaluation: an alternative approach to the two-year rodent bioassay

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices

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21 January 2018

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver

1 reference

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21 January 2018

Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Characteristic Expression Profiles Induced by Genotoxic Carcinogens in Rat Liver

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Comparative results of 327 chemical carcinogenicity studies

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Human carcinogenic risk evaluation, Part III: Assessing cancer hazard and risk in human drug development

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

1 reference

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21 January 2018

Complementarity of genotoxic and nongenotoxic predictors of rodent carcinogenicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Learning rules to predict rodent carcinogenicity of non-genotoxic chemicals.

1 reference

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21 January 2018

Relevance of animal carcinogenesis findings to human cancer predictions and prevention

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21 January 2018

The syrian hamster embryo (SHE) cell transformation assay: review of the methods and results

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21 January 2018

Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Genotoxic activity of praziquantel

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Erratum to "Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing".

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Use of short-term transcriptional profiles to assess the long-term cancer-related safety of environmental and industrial chemicals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Nonclinical safety evaluation of muraglitazar, a novel PPARalpha/gamma agonist

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFR202

21 January 2018

d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion

1 reference

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21 January 2018

Saccharin mechanistic data and risk assessment: urine composition, enhanced cell proliferation, and tumor promotion

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21 January 2018

Nongenotoxic carcinogens: development of detection methods based on mechanisms: a European project

1 reference

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21 January 2018

Identifiers

10.1093/TOXSCI/KFR202

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 November 2017

ResearchGate publication ID

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