(Q42732446)

English

Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome.

scientific article published on 19 May 2014

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

inflammasome complex

1 reference

based on heuristic

inferred from title

reactive oxygen species

1 reference

based on heuristic

inferred from title

3

1 reference

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18 March 2020

7

1 reference

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18 March 2020

author name string

Nathan A Bracey

1

1 reference

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18 March 2020

Benjamin Gershkovich

2

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18 March 2020

Akosua Vilaysane

4

1 reference

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18 March 2020

H Christopher Meijndert

5

1 reference

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18 March 2020

James R Wright

6

1 reference

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18 March 2020

Paul L Beck

8

1 reference

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18 March 2020

Daniel A Muruve

9

1 reference

Europe PubMed Central

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18 March 2020

Henry J Duff

10

1 reference

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18 March 2020

language of work or name

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publication date

19 May 2014

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18 March 2020

number of pages

14

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

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18 March 2020

289

1 reference

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18 March 2020

28

1 reference

Europe PubMed Central

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18 March 2020

19571-19584

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Physiological roles of mitochondrial reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Non-canonical inflammasome activation targets caspase-11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Myocardial remodeling after infarction: the role of myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The inflammasomes: guardians of the body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Role of mitochondria in angiotensin II-induced reactive oxygen species and mitogen-activated protein kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Essential role of Smad3 in angiotensin II-induced vascular fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

NLRs join TLRs as innate sensors of pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

Mechanism of activation of the TGF-beta receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

27 May 2018

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

16 August 2018

Cell therapy limits myofibroblast differentiation and structural cardiac remodeling: basic fibroblast growth factor-mediated paracrine mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

16 August 2018

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

16 August 2018

Superoxide mediates the actions of angiotensin II in the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

16 August 2018

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094069

16 August 2018

The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24841199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/24841199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of collagen production by transforming growth factor-beta1 during differentiation of cardiac fibroblasts to myofibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24841199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of lung fibroblast alpha-smooth muscle actin expression, contractile phenotype, and apoptosis by IL-1beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/24841199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/24841199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.550624

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24841199%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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