(Q42752579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21293487%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1 (English)

1 reference

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21 January 2020

0 references

1 reference

chronic lymphocytic leukemia

1 reference

1 reference

9

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21 January 2020

Ingo Ringshausen

11

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21 January 2020

author name string

S Huber

1

1 reference

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21 January 2020

M Oelsner

2

1 reference

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21 January 2020

T Decker

3

1 reference

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21 January 2020

C Meyer zum Büschenfelde

4

1 reference

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21 January 2020

M Wagner

5

1 reference

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21 January 2020

G Lutzny

6

1 reference

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21 January 2020

T Kuhnt

7

1 reference

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21 January 2020

B Schmidt

8

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21 January 2020

C Peschel

10

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21 January 2020

publication date

4 February 2011

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21 January 2020

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21 January 2020

volume

25

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21 January 2020

issue

5

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21 January 2020

page(s)

838-847

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https://scigraph.springernature.com/pub.10.1038/leu.2011.2

21 January 2020

exact match

0 references

cites work

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression

1 reference

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Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab

21 January 2018

1 reference

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Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

21 January 2018

1 reference

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Sorafenib in advanced clear-cell renal-cell carcinoma

21 January 2018

1 reference

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Sorafenib in advanced hepatocellular carcinoma

21 January 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

21 January 2018

1 reference

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Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.2

Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.2

Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia

21 January 2018

1 reference

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Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFC(week6) in extended long-term cultures

21 January 2018

1 reference

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Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.

21 January 2018

1 reference

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Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70.

21 January 2018

1 reference

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Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

21 January 2018

1 reference

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 January 2018

1 reference

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Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells.

21 January 2018

1 reference

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Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation

21 January 2018

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

21 January 2018

1 reference

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Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?

21 January 2018

1 reference

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Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27

21 January 2018

1 reference

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Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways

21 January 2018

1 reference

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Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

21 January 2018

1 reference

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ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

21 January 2018

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Strong correlation between VEGF and MCL-1 mRNA expression levels in B-cell chronic lymphocytic leukemia.

21 January 2018

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The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

21 January 2018

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Autocrine expression of platelet-derived growth factor B in B cell chronic lymphocytic leukemia.

21 January 2018

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Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

21 January 2018

1 reference

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Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors

21 January 2018

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Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

21 January 2018

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ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

21 January 2018

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7 January 2021

Regulation of clinical chemoresistance by bcl-2 and bax oncoproteins in B-cell chronic lymphocytic leukaemia

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7 January 2021

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

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7 January 2021

All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells

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7 January 2021

Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity

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7 January 2021

Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells

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7 January 2021

Proliferation centres in B-cell malignant lymphoma, lymphocytic (B-CLL): an immunophenotypic study

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7 January 2021

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

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7 January 2021

Identifiers

DOI

10.1038/LEU.2011.2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21293487%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 January 2020

1028195451

0 references

1 reference