(Q42756844)

English

Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop

scientific article published on February 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop (English)

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

author name string

Chen Yan

1

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Bo Ding

2

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Tetsuro Shishido

3

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Chang-Hoon Woo

4

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Seigo Itoh

5

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Kye-Im Jeon

6

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Weimin Liu

7

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Haodong Xu

8

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Carolyn McClain

9

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Carlos A Molina

10

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Burns C Blaxall

11

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Jun-ichi Abe

12

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

publication date

1 February 2007

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Circulation Research

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

100

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

4

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

510-519

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Akt1 in the cardiovascular system: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Inducible cAMP early repressor (ICER) in the nervous system--a transcriptional regulator of neuronal plasticity and programmed cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

What is the role of beta-adrenergic signaling in heart failure?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Mitogen-activated protein kinase phosphorylates and targets inducible cAMP early repressor to ubiquitin-mediated destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Left ventricular hypertrophy in ascending aortic stenosis mice: anoikis and the progression to early failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Apoptosis and heart failure: A critical review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Big mitogen-activated kinase regulates multiple members of the MEF2 protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Insulin-like growth factor-1 and myocyte growth: the danger of a dogma. Part I. Postnatal myocardial development: normal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Components of a new human protein kinase signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Primary Structure of BMK1: A New Mammalian MAP Kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

27 May 2018

Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Inducible cAMP early repressor (ICER) is a negative-feedback regulator of cardiac hypertrophy and an important mediator of cardiac myocyte apoptosis in response to beta-adrenergic receptor stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-bi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115673

16 August 2018

Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17272811

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17272811

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the failing human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17272811

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/01.RES.0000259045.49371.9C

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

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