(Q42761664)

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Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1.

scientific article published on 26 May 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1. (English)

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Amarnath Natarajan

4

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

author name string

Ziyan Yuan

1

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Eric A Kumar

2

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Smitha Kizhake

3

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

language of work or name

0 references

publication date

26 May 2011

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

54

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

12

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

4264-4268

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structural characterization of BRCT-tetrapeptide binding interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

BRCA1 and its toolbox for the maintenance of genome integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

A thermodynamic approach to the affinity optimization of drug candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Small-molecule inhibitors of protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Chemical genetics to chemical genomics: small molecules offer big insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

27 May 2018

High-throughput fluorescence polarization assay to identify small molecule inhibitors of BRCT domains of breast cancer gene 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

16 August 2018

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

16 August 2018

Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117075

16 August 2018

Poly-L-proline type II peptide mimics as probes of the active site occupancy requirements of cGMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21574625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design

1 reference

https://pubmed.ncbi.nlm.nih.gov/21574625

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM1016413

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 November 2017

ResearchGate publication ID

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