(Q42770411)

English

Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9.

scientific article published on 29 April 2011

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scholarly article

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Europe PubMed Central

PMC publication ID

7 November 2017

Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9. (English)

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

phosphorylation

1 reference

based on heuristic

inferred from title

Johan M. Thevelein

6

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

author name string

Karin Voordeckers

1

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Marlies Kimpe

2

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Steven Haesendonckx

3

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Wendy Louwet

4

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Matthias Versele

5

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

language of work or name

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publication date

29 April 2011

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

7 November 2017

286

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Europe PubMed Central

PMC publication ID

7 November 2017

25

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

22017-22027

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

The nuts and bolts of AGC protein kinases

1 reference

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27 May 2018

A protein kinase network regulates the function of aminophospholipid flippases

1 reference

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27 May 2018

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

1 reference

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27 May 2018

Caffeine extends yeast lifespan by targeting TORC1.

1 reference

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27 May 2018

TOR regulation of AGC kinases in yeast and mammals

1 reference

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27 May 2018

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

1 reference

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27 May 2018

Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast.

1 reference

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27 May 2018

Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4

1 reference

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27 May 2018

Using substrate-binding variants of the cAMP-dependent protein kinase to identify novel targets and a kinase domain important for substrate interactions in Saccharomyces cerevisiae

1 reference

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27 May 2018

The molecular chaperone Sse1 and the growth control protein kinase Sch9 collaborate to regulate protein kinase A activity in Saccharomyces cerevisiae.

1 reference

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27 May 2018

Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

1 reference

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27 May 2018

In vivo activation of protein kinase A in Schizosaccharomyces pombe requires threonine phosphorylation at its activation loop and is dependent on PDK1

1 reference

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A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

1 reference

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27 May 2018

Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

1 reference

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27 May 2018

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Phosphorylation of the catalytic subunit of protein kinase A. Autophosphorylation versus phosphorylation by phosphoinositide-dependent kinase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Systematic identification of pathways that couple cell growth and division in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Regulation of longevity and stress resistance by Sch9 in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

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27 May 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

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Active and inactive protein kinases: structural basis for regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

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In yeast, RAS proteins are controlling elements of adenylate cyclase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

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Association of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase requires a negatively charged side group at a conserved threonine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

27 May 2018

Autophosphorylation of the catalytic subunit of cAMP-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

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Sequence of two phosphorylated sites in the catalytic subunit of bovine cardiac muscle adenosine 3‘:5‘-monophosphate-dependent protein kinase

1 reference

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Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor

1 reference

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16 August 2018

Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

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Glucose-dependent activation of protein kinase A activity in Saccharomyces cerevisiae and phosphorylation of its TPK1 catalytic subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121346

16 August 2018

The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.

1 reference

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The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae

1 reference

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Identification of phosphorylation sites in the recombinant catalytic subunit of cAMP-dependent protein kinase.

1 reference

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16 August 2018

cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.200071

21 January 2018

Nutrient-induced activation of trehalase in nutrient-starved cells of the yeast Saccharomyces cerevisiae: cAMP is not involved as second messenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/21531713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of trehalase during growth induction by nitrogen sources in the yeast Saccharomyces cerevisiae depends on the free catalytic subunits of cAMP-dependent protein kinase, but not on functional Ras proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21531713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21531713

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.200071

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

7 November 2017

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