(Q42799714)

English

RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

scientific article published on October 2000

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scholarly article

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8 November 2019

RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription (English)

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8 November 2019

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8 November 2019

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8 November 2019

author name string

Couderc B

3

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8 November 2019

Salicio S

4

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8 November 2019

Sixou S

5

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8 November 2019

Hamilton AD

6

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8 November 2019

Sebti SM

7

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8 November 2019

Lajoie-Mazenc I

8

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8 November 2019

Pradines A

9

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8 November 2019

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publication date

1 October 2000

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8 November 2019

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8

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Journal of Biological Chemistry

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8 November 2019

275

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8 November 2019

31001-31008

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8 November 2019

40

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8 November 2019

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Microinjection of recombinant p21rho induces rapid changes in cell morphology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

ADP-ribosylation of the GTP-binding protein RhoA blocks cytoplasmic division in human myelomonocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Quantitation of prenylcysteines by a selective cleavage reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Protein prenylation: molecular mechanisms and functional consequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Membrane association and targeting of prenylated Ras-like GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Intracellular localization of the P21rho proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Synergistic activation of rat brain phospholipase D by ADP-ribosylation factor and rhoA p21, and its inhibition by Clostridium botulinum C3 exoenzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Regulation of phospholipase D by low molecular weight GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

The small GTP-binding protein Rho potentiates AP-1 transcription in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Specific isoprenyl group linked to transducin gamma-subunit is a determinant of its unique signaling properties among G-proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Role of isoprenoid lipids on the heterotrimeric G protein gamma subunit in determining effector activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Improved oligonucleotide uptake and stability by a new drug carrier, the SupraMolecular Bio Vector (SMBV).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

A study of the Influence of mevalonic acid and its metabolites on the morphology of swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Regulation of intracellular actin polymerization by prenylated cellular proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Mevalonate controls cytoskeleton organization and cell morphology in thyroid epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005264200

21 January 2018

Identifiers

10.1074/JBC.M005264200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896672%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10896672%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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