(Q42801886)

7 November 2017

title

Leucine zipper-mediated dimerization is essential for the PTC1 oncogenic activity (English)

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7 November 2017

Tong Q

1

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7 November 2017

Xing S

series ordinal

2

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7 November 2017

Jhiang SM

series ordinal

3

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7 November 2017

language of work or name

English

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publication date

1 April 1997

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

272

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7 November 2017

issue

14

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7 November 2017

page(s)

9043-9047

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PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

7 November 2017

cites work

1 reference

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Functional receptor for GDNF encoded by the c-ret proto-oncogene

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Characterization of a multicomponent receptor for GDNF.

21 January 2018

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GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

21 January 2018

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Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

21 January 2018

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Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

21 January 2018

1 reference

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Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease

21 January 2018

1 reference

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Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours

21 January 2018

1 reference

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A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

21 January 2018

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Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells

21 January 2018

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Signal transduction by receptors with tyrosine kinase activity

21 January 2018

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Loss of function effect of RET mutations causing Hirschsprung disease.

21 January 2018

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Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A

21 January 2018

1 reference

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Development of a single-step duplex RT-PCR detecting different forms of ret activation, and identification of the third form of in vivo ret activation in human papillary thyroid carcinoma

21 January 2018

1 reference

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Tyrosines outside the kinase core and dimerization are required for the mitogenic activity of RET/ptc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9043

ret transforming gene encodes a fusion protein homologous to tyrosine kinases

21 January 2018

1 reference

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Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.14.9043

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

1 reference

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A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

21 January 2018

1 reference

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A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.14.9043

1 reference

7 November 2017

1 reference