(Q42803654)

7 November 2017

Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation (English)

1 reference

7 November 2017

R A Rimerman

1

1 reference

7 November 2017

A Gellert-Randleman

series ordinal

2

1 reference

7 November 2017

J A Diehl

series ordinal

3

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7 November 2017

language of work or name

English

0 references

publication date

1 May 2000

1 reference

Journal of Biological Chemistry

7 November 2017

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7 November 2017

275

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7 November 2017

14736-14742

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7 November 2017

19

1 reference

WNTs modulate cell fate and behavior during vertebrate development

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Signal transduction by the Wnt family of ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

D-type cyclin-dependent kinase activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Identification of protein products encoded by the proto-oncogene int-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Association of the APC gene product with beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910241199

21 January 2018

Identifiers

DOI

10.1074/JBC.M910241199

1 reference

7 November 2017

1 reference