(Q42804390)

English

ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate

scientific article published on January 1997

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scholarly article

1 reference

Europe PubMed Central

7 November 2017

ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate (English)

1 reference

Europe PubMed Central

7 November 2017

author name string

T Chung

1

1 reference

Europe PubMed Central

7 November 2017

K S Crilly

2

1 reference

Europe PubMed Central

7 November 2017

W H Anderson

3

1 reference

Europe PubMed Central

7 November 2017

J J Mukherjee

4

1 reference

Europe PubMed Central

7 November 2017

Z Kiss

5

1 reference

Europe PubMed Central

7 November 2017

language of work or name

0 references

publication date

1 January 1997

1 reference

Europe PubMed Central

7 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

7 November 2017

272

1 reference

Europe PubMed Central

7 November 2017

3064-3072

1 reference

Europe PubMed Central

7 November 2017

5

1 reference

Europe PubMed Central

7 November 2017

Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Epidermal growth factor-induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Synergistic potentiating effects of choline phosphate and ethanolamine on insulin-induced DNA synthesis in NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Biological response to phorbol ester determined by alternative G1 pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Homologous desensitization of ATP-stimulated mitogenesis: mechanism involves desensitization of arachidonic acid release and cAMP elevation but not the activation of protein kinase A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorbol 13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Overexpression of protein kinase C-epsilon enhances the stimulatory effect of ethanol on phospholipase C-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Activation of MAP kinase and enhanced phosphorylation of the 350-kDa protein by mitogenic stimuli in quiescent Balb/c 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Structure, regulation and function of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Wortmannin inhibits mitogen-activated protein kinase activation by platelet-activating factor through a mechanism independent of p85/p110-type phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Wortmannin has opposite effects on phorbol ester-induced DNA synthesis and phosphatidylcholine hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Extracellular ATP induces the release of calcium from intracellular stores without the activation of protein kinase C in Swiss 3T6 mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Epidermal growth factor and bombesin differ strikingly in the induction of early responses in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Mitogenesis in response to PDGF and bombesin abolished by microinjection of antibody to PIP2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Functional expression and photoaffinity labeling of a cloned P2U purinergic receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Extracellular ATP: effects, sources and fate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

p70s6k/p85s6k: mechanism of activation, effects of rapamycin and role in mitogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Wortmannin inhibits carcinogen-stimulated phosphorylation of ethanolamine and choline

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Ha-Ras stimulates uptake and phosphorylation of ethanolamine: inhibition by wortmannin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

p70s6k function is essential for G1 progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Hepatocyte growth factor (HGF) mediates the sustained formation of 1,2-diacylglycerol via phosphatidylcholine-phospholipase C in cultured rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Induction of choline kinase by polycyclic aromatic hydrocarbon carcinogens in rat liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

The effect of polycyclic aromatic hydrocarbons on choline kinase activity in mouse hepatoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.3064

21 January 2018

Identifiers

10.1074/JBC.272.5.3064

1 reference

Europe PubMed Central

7 November 2017

1 reference

Europe PubMed Central

7 November 2017

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