(Q42816817)

7 November 2017

title

The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1. (English)

1 reference

7 November 2017

Frank RC

1

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7 November 2017

Sun X

2

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7 November 2017

Berguido FJ

3

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7 November 2017

Jakubowiak A

4

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7 November 2017

Nimer SD

5

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7 November 2017

language of work or name

English

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publication date

1 March 1999

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7 November 2017

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7 November 2017

volume

18

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7 November 2017

issue

9

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7 November 2017

page(s)

1701-1710

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202459

7 November 2017

exact match

0 references

cites work

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Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

21 January 2018

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Leukaemia/Drosophila homology

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Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells

21 January 2018

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Induction of apoptosis in fibroblasts by c-myc protein

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Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein

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Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt

21 January 2018

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

21 January 2018

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The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

21 January 2018

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AP-1 function and regulation

21 January 2018

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The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

21 January 2018

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The AML1/ETO fusion protein activates transcription of BCL-2

21 January 2018

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

21 January 2018

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Transformation suppressor activity of a Jun transcription factor lacking its activation domain

21 January 2018

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The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

21 January 2018

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Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

21 January 2018

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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

21 January 2018

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

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Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

21 January 2018

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Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

21 January 2018

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Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor

21 January 2018

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

21 January 2018

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

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What's up and down with histone deacetylation and transcription?

21 January 2018

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Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

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The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

21 January 2018

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The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation

21 January 2018

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

21 January 2018

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Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

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Molecular genetics of acute leukaemia

21 January 2018

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

21 January 2018

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Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

21 January 2018

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Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias

21 January 2018

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

21 January 2018

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

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The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202459

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

21 January 2018

1 reference

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Transcriptional control. Sinful repression

21 January 2018

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Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

21 January 2018

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E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF.

21 January 2018

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The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

21 January 2018

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7 January 2021

Indirect and direct disruption of transcriptional regulation in cancer: E2F and AML-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202459

7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202459

7 January 2021

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202459

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202459

1 reference

Dimensions Publication ID

7 November 2017

1045912171

0 references

1 reference