(Q42818357)

English

Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C.

scientific article published on October 1988

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scholarly article

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Europe PubMed Central

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11 October 2019

Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3143357%20AND%20SRC:MED&resulttype=core&format=json

11 October 2019

platelet aggregation

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author name string

Siess W

1

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11 October 2019

Lapetina EG

2

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Europe PubMed Central

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11 October 2019

language of work or name

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publication date

1 October 1988

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Europe PubMed Central

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11 October 2019

Biochemical Journal

1 reference

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11 October 2019

255

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11 October 2019

1

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11 October 2019

309-318

1 reference

Europe PubMed Central

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11 October 2019

Interaction of Ca2+ and protein phosphorylation in the rabbit platelet release reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Receptor-mediated modulation of human monocyte, neutrophil, lymphocyte, and platelet function by phorbol diesters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Evidence for a role of myosin phosphorylation in the initiation of the platelet shape change response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

The role of cytoplasmic free calcium in the responses of quin2-loaded human platelets to vasopressin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Regulation of contractile proteins by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Dihomogammalinolenic acid, but not eicosapentaenoic acid, activates washed human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Responses to adenosine diphosphate in human platelets loaded with the fluorescent calcium indicator quin2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Lack of inhibition of thrombin-induced rise in intracellular Ca2+ levels and 5-hydroxytryptamine secretion by 1-oleoyl-2-acetylglycerol in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Platelet activating factor raises intracellular calcium ion concentration in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

ADP stimulates IP3 formation in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Studies and perspectives of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Activation of V1-receptors by vasopressin stimulates inositol phospholipid hydrolysis and arachidonate metabolism in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Tumour-promoting phorbol esters inhibit agonist-induced phosphatidate formation and Ca2+ flux in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Synergistic potentiation of 5-hydroxytryptamine secretion by platelet agonists and phorbol myristate acetate despite inhibition of agonist-induced arachidonate/thromboxane and beta-thromboglobulin release and Ca2+ mobilization by phorbol myristate a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Nonreversible loss of platelet aggregability induced by calcium deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1135224

27 May 2018

Phorbol esters sensitize platelets to activation by physiological agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ -calmodulin-dependent phosphorylation and platelet secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ mobilization in blood platelets as visualized by chlortetracycline fluorescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shape change induced in human platelets by platelet-activating factor. Correlation with the formation of phosphatidic acid and phosphorylation of a 40,000-dalton protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP inhibits platelet activation independently of its effect on cytosolic free calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and functional consequences of dissociation of the platelet membrane glycoprotein IIb-IIIa complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of tetradecanoylphorbol acetate on calcium-ion mobilization, protein phosphorylation and cytoskeletal assembly induced by thrombin or arachidonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol esters modulate thrombin-operated calcium mobilisation and dense granule release in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic differences between thrombin-induced and ADP-induced calcium influx and release from internal stores in fura-2-loaded human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The modulatory role of myosin light chain phosphorylation in human platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of 12-O-tetradecanoylphorbol 13-acetate on platelet responses to various agonists in the presence and absence of extracellular Ca2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/3143357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3143357%20AND%20SRC:MED&resulttype=core&format=json

11 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3143357%20AND%20SRC:MED&resulttype=core&format=json

11 October 2019

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