(Q42823414)

English

The v-sis oncogene product but not platelet-derived growth factor (PDGF) A homodimers activate PDGF alpha and beta receptors intracellularly and initiate cellular transformation

scientific article published on February 15, 1992

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Europe PubMed Central

8 November 2017

The v-sis oncogene product but not platelet-derived growth factor (PDGF) A homodimers activate PDGF alpha and beta receptors intracellularly and initiate cellular transformation (English)

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11 September 2022

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11 September 2022

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10.1016/S0021-9258(19)50729-3

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1 December 2023

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10.1016/S0021-9258(19)50729-3

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author name string

B. E. Bejcek

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11 September 2022

R. M. Hoffman

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11 September 2022

D. Lipps

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11 September 2022

D. Y. Li

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11 September 2022

C. A. Mitchell

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11 September 2022

P. W. Majerus

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11 September 2022

T. F. Deuel

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11 September 2022

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publication date

1 February 1992

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8 November 2017

15 February 1992

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11 September 2022

full work available at URL

http://intl.jbc.org/cgi/content/abstract/267/5/3289

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11 September 2022

https://doi.org/10.1016/s0021-9258(19)50729-3

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1 December 2023

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1 December 2023

Journal of Biological Chemistry

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8 November 2017

267

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8 November 2017

5

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Europe PubMed Central

8 November 2017

3289-3293

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Europe PubMed Central

8 November 2017

Polypeptide growth factors: roles in normal and abnormal cell growth

1

1 reference

10.1016/S0021-9258(19)50729-3

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cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

2

1 reference

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cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains

3

1 reference

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1 December 2023

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

4

1 reference

10.1016/S0021-9258(19)50729-3

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Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

5

1 reference

10.1016/S0021-9258(19)50729-3

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1 December 2023

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor

6

1 reference

10.1016/S0021-9258(19)50729-3

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Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor

7

1 reference

10.1016/S0021-9258(19)50729-3

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Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor

8

1 reference

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1 December 2023

Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains

9

1 reference

10.1016/S0021-9258(19)50729-3

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Two classes of PDGF receptor recognize different isoforms of PDGF

11

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Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes

13

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1 December 2023

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

15

1 reference

10.1016/S0021-9258(19)50729-3

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1 December 2023

Molecular localization of the transforming and secretory properties of PDGF A and PDGF B.

16

1 reference

10.1016/S0021-9258(19)50729-3

https://api.crossref.org/works/10.1016/S0021-9258(19)50729-3

1 December 2023

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

17

1 reference

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1 December 2023

Transformation by v-sis occurs by an internal autoactivation mechanism

18

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A new technique for the assay of infectivity of human adenovirus 5 DNA

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Molecular cloning and comparative analyses of the genomes of simian sarcoma virus and its associated helper virus

20

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Cell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transport

21

1 reference

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1 December 2023

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

23

1 reference

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Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells

26

1 reference

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Association between the PDGF receptor and members of the src family of tyrosine kinases

27

1 reference

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Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

28

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Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C

29

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

33

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10.1016/S0021-9258(19)50729-3

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Binding of GAP to activated PDGF receptors

34

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10.1016/S0021-9258(19)50729-3

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PDGF induction of tyrosine phosphorylation of GTPase activating protein

35

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10.1016/S0021-9258(19)50729-3

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

36

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10.1016/S0021-9258(19)50729-3

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Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

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Autocrine secretion and malignant transformation of cells.

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

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Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface

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Europe PubMed Central

8 November 2017

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