(Q42826746)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15284236%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity (English)

1 reference

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31 December 2019

5

1 reference

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31 December 2019

Rainer Heuchel

10

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31 December 2019

Federica Chiara

1

1 reference

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31 December 2019

author name string

Marie-José Goumans

2

1 reference

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31 December 2019

Henrik Forsberg

3

1 reference

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31 December 2019

Aive Ahgrén

4

1 reference

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31 December 2019

Pontus Aspenström

6

1 reference

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31 December 2019

Christer Wernstedt

7

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31 December 2019

Carina Hellberg

8

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31 December 2019

Carl-Henrik Heldin

9

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31 December 2019

language of work or name

English

0 references

publication date

28 July 2004

1 reference

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Journal of Biological Chemistry

31 December 2019

published in

1 reference

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31 December 2019

volume

279

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31 December 2019

issue

41

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31 December 2019

page(s)

42516-42527

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Signaling through scaffold, anchoring, and adaptor proteins

31 December 2019

cites work

1 reference

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Protein tyrosine kinase structure and function

21 January 2018

1 reference

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Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes

21 January 2018

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PDGFRA activating mutations in gastrointestinal stromal tumors.

21 January 2018

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Activating c-kit gene mutations in human germ cell tumors

21 January 2018

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

1 reference

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Mutations in the met oncogene unveil a "dual switch" mechanism controlling tyrosine kinase activity

21 January 2018

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Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

21 January 2018

1 reference

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

21 January 2018

1 reference

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Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways

21 January 2018

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Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

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Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

21 January 2018

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A flow cytometry assay simultaneously detects independent apoptotic parameters

21 January 2018

1 reference

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Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

21 January 2018

1 reference

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Oncogenic kinase signalling

21 January 2018

1 reference

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Full activation of the platelet-derived growth factor beta-receptor kinase involves multiple events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406051200

Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406051200

Platelet-derived growth factor-dependent cellular transformation requires either phospholipase Cgamma or phosphatidylinositol 3 kinase

21 January 2018

1 reference

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

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Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.

21 January 2018

1 reference

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Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406051200

SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406051200

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

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Phosphatidylinositol 3 kinase contributes to the transformation of hematopoietic cells by the D816V c-Kit mutant

21 January 2018

1 reference

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Non-injection methods for the production of embryonic stem cell-embryo chimaeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406051200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406051200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15284236%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference