(Q42830201)

8 November 2017

RUNX1-RUNX1 homodimerization modulates RUNX1 activity and function (English)

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8 November 2017

2

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8 November 2017

Donglan Li

1

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8 November 2017

Maher A Hay

3

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8 November 2017

Ciro R Rinaldi

4

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8 November 2017

Yogen Saunthararajah

5

1 reference

8 November 2017

Giuseppina Nucifora

6

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8 November 2017

language of work or name

English

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publication date

13 March 2007

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

282

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8 November 2017

18

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8 November 2017

13542-13551

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Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Conservation and function of the transcriptional regulatory protein Runt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor alpha subunit revealed in the presence of the beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Groucho-dependent and -independent repression activities of Runt domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

AML1 gene over-expression in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Normal and transforming functions of RUNX1: a perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Oligomerization of ETO is obligatory for corepressor interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Combinatorial action of RUNX1 and PU.1 in the regulation of hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700074200

21 January 2018

Identifiers

DOI

10.1074/JBC.M700074200

1 reference

8 November 2017

1 reference