(Q42830333)

8 November 2017

title

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme (English)

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8 November 2017

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3

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8 November 2017

Partha Krishnamurthy

1

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8 November 2017

Douglas D Ross

2

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8 November 2017

Kim Bailey-Dell

4

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8 November 2017

Sheng Zhou

5

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8 November 2017

Kelly E Mercer

6

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8 November 2017

Balazs Sarkadi

7

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8 November 2017

Brian P Sorrentino

8

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8 November 2017

John D Schuetz

9

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8 November 2017

language of work or name

English

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publication date

24 March 2004

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Journal of Biological Chemistry

8 November 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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8 November 2017

volume

279

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8 November 2017

issue

23

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8 November 2017

page(s)

24218-24225

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

8 November 2017

cites work

1 reference

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Tissue-based stem cells: ABC transporter proteins take centre stage

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Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells

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Hypoxic up-regulation of erythroid 5-aminolevulinate synthase

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

21 January 2018

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The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

21 January 2018

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ABC transporters as phenotypic markers and functional regulators of stem cells

21 January 2018

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Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

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Low levels of ABCG2 expression in adult AML blast samples

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Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma

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Fluorescence detection of small gastrointestinal tumours: principles, technique, first clinical experience

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Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

21 January 2018

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Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

21 January 2018

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Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

21 January 2018

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Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway

21 January 2018

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Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

21 January 2018

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A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

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Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance

21 January 2018

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Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase

21 January 2018

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Analysis of photoaffinity-labeled aryl hydrocarbon receptor heterogeneity by two-dimensional gel electrophoresis

21 January 2018

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DNA binding properties of the Ah receptor in wild-type and variant mouse hepatoma cells

21 January 2018

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Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin.

21 January 2018

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The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties

21 January 2018

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Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage

21 January 2018

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21 January 2018

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Multidrug resistance and cancer: the role of the human ABC transporter ABCG2.

21 January 2018

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The role of half-transporters in multidrug resistance

21 January 2018

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Novel mechanisms of drug resistance in leukemia

21 January 2018

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Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation

21 January 2018

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ABCG2 transports sulfated conjugates of steroids and xenobiotics

21 January 2018

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Differential Modulation of the Human Liver Conjugate Transporters MRP2 and MRP3 by Bile Acids and Organic Anions

21 January 2018

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Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(+)CD38(-) progenitor cells from patients with acute myeloid leukemia

21 January 2018

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A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia

21 January 2018

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M313599200

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8 November 2017

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