(Q42830397)

English

Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397.

scientific article published on 15 February 2001

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scholarly article

1 reference

Europe PubMed Central

8 November 2017

Src family kinases are required for integrin-mediated but not for G protein-coupled receptor stimulation of focal adhesion kinase autophosphorylation at Tyr-397. (English)

1 reference

Europe PubMed Central

8 November 2017

G protein-coupled receptor

0 references

author name string

Salazar EP

1

1 reference

Europe PubMed Central

8 November 2017

Rozengurt E

2

1 reference

Europe PubMed Central

8 November 2017

language of work or name

0 references

publication date

15 February 2001

1 reference

Europe PubMed Central

8 November 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

8 November 2017

276

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Europe PubMed Central

8 November 2017

17788-17795

1 reference

Europe PubMed Central

8 November 2017

21

1 reference

Europe PubMed Central

8 November 2017

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesion kinase and associated proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Tyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3'-kinase and formation of a p130(Cas).Crk complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Dissociation of mitogen-activated protein kinase activation from p125 focal adhesion kinase tyrosine phosphorylation in Swiss 3T3 cells stimulated by bombesin, lysophosphatidic acid, and platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesions, contractility, and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Src family kinases are required for integrin but not PDGFR signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Focal adhesion kinase promotes phospholipase C-gamma1 activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Association of focal adhesion kinase with Grb7 and its role in cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Protein modules and signalling networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100984200

21 January 2018

Identifiers

10.1074/JBC.M100984200

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

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