(Q42830556)

8 November 2017

title

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes (English)

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8 November 2017

Alexandro Membrino

1

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8 November 2017

Manikandan Paramasivam

2

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8 November 2017

Susanna Cogoi

3

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8 November 2017

Jawad Alzeer

4

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8 November 2017

Nathan W Luedtke

5

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8 November 2017

Luigi E Xodo

6

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8 November 2017

language of work or name

English

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publication date

20 November 2009

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8 November 2017

published in

Chemical Communications

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8 November 2017

volume

46

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8 November 2017

issue

4

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8 November 2017

page(s)

625-627

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Gene function correlates with potential for G4 DNA formation in the human genome

8 November 2017

cites work

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Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

21 January 2018

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G-quadruplexes in promoters throughout the human genome

21 January 2018

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Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation

21 January 2018

1 reference

An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

21 January 2018

1 reference

An unusually stable G-quadruplex within the 5'-UTR of the MT3 matrix metalloproteinase mRNA represses translation in eukaryotic cells

21 January 2018

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G-quadruplex structures: in vivo evidence and function

21 January 2018

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

21 January 2018

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Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands

21 January 2018

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A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression

21 January 2018

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G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

21 January 2018

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Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

21 January 2018

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Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

21 January 2018

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The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.

21 January 2018

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A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

21 January 2018

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Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.

21 January 2018

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G-quadruplex nucleic acids as therapeutic targets

21 January 2018

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The structures of quadruplex nucleic acids and their drug complexes

21 January 2018

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A hitchhiker's guide to G-quadruplex ligands

21 January 2018

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G-quadruplexes: targets in anticancer drug design.

21 January 2018

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Use of competition dialysis in the discovery of G-quadruplex selective ligands.

21 January 2018

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Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands.

21 January 2018

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Synthesis and evaluation of cationic phthalocyanine derivatives as potential inhibitors of telomerase

21 January 2018

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Biophysical studies of the c-MYC NHE III1 promoter: model quadruplex interactions with a cationic porphyrin

21 January 2018

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Structural basis for binding of porphyrin to human telomeres

21 January 2018

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An efficient two-step synthesis of metal-free phthalocyanines using a Zn(ii) template

21 January 2018

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An S1 nuclease-sensitive homopurine/homopyrimidine domain in the c-Ki-ras promoter interacts with a nuclear factor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/B918964E

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8 November 2017

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