(Q42832843)

8 November 2017

The insulin receptor substrate (IRS)-1 pleckstrin homology domain functions in downstream signaling (English)

1 reference

8 November 2017

1 reference

Vainshtein I

1

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8 November 2017

Kovacina KS

series ordinal

2

1 reference

8 November 2017

Roth RA

series ordinal

3

1 reference

8 November 2017

language of work or name

English

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publication date

5 January 2001

1 reference

Journal of Biological Chemistry

8 November 2017

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8 November 2017

276

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8 November 2017

8073-8078

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8 November 2017

11

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Signaling pathways in insulin action: molecular targets of insulin resistance

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Activation of phosphatidylinositol 3-kinase by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

The pleckstrin homology domain: an intriguing multifunctional protein module

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

PTB domain of insulin receptor substrate-1 binds inositol compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

IRS pleckstrin homology domains bind to acidic motifs in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

The PI/PTB domain: a new protein interaction domain involved in growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Interaction between the insulin receptor and its downstream effectors. Use of individually expressed receptor domains for structure/function analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Heterologous pleckstrin homology domains do not couple IRS-1 to the insulin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008436200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008436200

1 reference

8 November 2017

1 reference