(Q42850400)

8 November 2017

Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease (English)

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metabolic dysfunction–associated steatotic liver disease

8 November 2017

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9

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8 November 2017

11

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8 November 2017

Marcos Martínez-Clemente

1

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8 November 2017

Natàlia Ferré

2

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8 November 2017

Esther Titos

3

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8 November 2017

Raquel Horrillo

4

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8 November 2017

Ana González-Périz

5

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8 November 2017

Eva Morán-Salvador

6

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8 November 2017

Cristina López-Vicario

7

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8 November 2017

Rosa Miquel

8

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8 November 2017

Colin D Funk

10

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8 November 2017

language of work or name

English

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publication date

21 October 2010

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8 November 2017

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8 November 2017

52

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8 November 2017

6

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8 November 2017

1980-1991

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Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice

8 November 2017

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A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II.

21 January 2018

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Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells

21 January 2018

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Overexpression of 12-lipoxygenase causes cardiac fibroblast cell growth

21 January 2018

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Evidence that angiotensin II and lipoxygenase products activate c-Jun NH2-terminal kinase

21 January 2018

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Abnormalities of lipid metabolism in nonalcoholic fatty liver disease

21 January 2018

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7 January 2021

Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications

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7 January 2021

Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population

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7 January 2021

Prevalence and etiology of altered liver tests: a population-based survey in a Mediterranean town

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7 January 2021

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

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7 January 2021

5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor alpha-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice.

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7 January 2021

Inflammation and immune regulation by 12/15-lipoxygenases

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7 January 2021

Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity

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7 January 2021

12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes.

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7 January 2021

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

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7 January 2021

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice

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7 January 2021

Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

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7 January 2021

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice

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7 January 2021

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

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7 January 2021

The plasma lipidomic signature of nonalcoholic steatohepatitis

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7 January 2021

Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

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7 January 2021

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

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7 January 2021

Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins

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7 January 2021

Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis

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7 January 2021

Inhibition of 5-lipoxygenase induces cell growth arrest and apoptosis in rat Kupffer cells: implications for liver fibrosis

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7 January 2021

Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells

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7 January 2021

Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes

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7 January 2021

The transport of triglycerides through the secretory pathway of hepatocytes is impaired in apolipoprotein E deficient mice

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7 January 2021

Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes

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7 January 2021

Pathophysiological roles of interleukin-18 in inflammatory liver diseases

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7 January 2021

Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.

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7 January 2021

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

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7 January 2021

NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis.

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7 January 2021

Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability

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7 January 2021

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome

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7 January 2021

Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver

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7 January 2021

Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice

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7 January 2021

Therapeutic targets in liver transplantation: angiotensin II in nonsteatotic grafts and angiotensin-(1-7) in steatotic grafts.

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7 January 2021

Insulin resistance, inflammation, and non-alcoholic fatty liver disease

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7 January 2021

Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma

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7 January 2021

The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophages

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7 January 2021

Role of specific isoforms of protein kinase C in angiotensin II and lipoxygenase action in rat adrenal glomerulosa cells

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7 January 2021

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability

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7 January 2021

Identifiers

DOI

10.1002/HEP.23928

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8 November 2017

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