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English
Shock and awe: unleashing the heat shock response to treat Huntington disease.
scientific article published on 25 July 2011
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
editorial
0 references
title
Shock and awe: unleashing the heat shock response to treat Huntington disease
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
main subject
Huntington's disease
0 references
author
Meredith Jackrel
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
James Shorter
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author name string
Meredith E Jackrel
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
retrieved
8 November 2017
James Shorter
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
retrieved
8 November 2017
language of work or name
English
0 references
publication date
25 July 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
volume
121
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
page(s)
2972-2975
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
cites work
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
27 May 2018
Huntington's disease: can mice lead the way to treatment?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
27 May 2018
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Emergence and natural selection of drug-resistant prions
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PubMed Central
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27 May 2018
Prion-like disorders: blurring the divide between transmissibility and infectivity
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PubMed Central
reference URL
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27 May 2018
Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease
1 reference
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PubMed Central
reference URL
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27 May 2018
Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
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PubMed Central
reference URL
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27 May 2018
Biological and chemical approaches to diseases of proteostasis deficiency
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
27 May 2018
Chemical and biological approaches synergize to ameliorate protein-folding diseases.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
27 May 2018
Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
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PubMed Central
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27 May 2018
Adapting proteostasis for disease intervention
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
27 May 2018
Heat shock response modulators as therapeutic tools for diseases of protein conformation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Hsp90 and chromatin: where is the link?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Geldanamycin restores a defective heat shock response in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
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27 May 2018
Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach
1 reference
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PubMed Central
reference URL
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16 August 2018
Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.
1 reference
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PubMed Central
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16 August 2018
Pharmacological prevention of Parkinson disease in Drosophila.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
16 August 2018
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
16 August 2018
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
16 August 2018
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148752
retrieved
16 August 2018
Identifiers
DOI
10.1172/JCI59190
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMC publication ID
3148752
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed publication ID
21785212
1 reference
stated in
Europe PubMed Central
PMC publication ID
3148752
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21785212%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
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