(Q42873292)

English

An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

scientific article published on September 29, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid tumors (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors (English)

1 reference

10.1038/CLPT.2010.158

https://api.crossref.org/works/10.1038/CLPT.2010.158

23 July 2024

0 references

cytochrome P-450 enzyme inhibitors

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

author name string

C-F Xu

10

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

B. C. Goh

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

N. J. Reddy

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

U. B. Dandamudi

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

K. H. Laubscher

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

T. Peckham

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

J. P. Hodge

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

A. B. Suttle

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

T. Arumugham

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

Y. Xu

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

J. Lager

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

M. M. Dar

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

L. D. Lewis

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20881954

23 July 2024

language of work or name

0 references

publication date

29 September 2010

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

Clinical Pharmacology & Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

88

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

652-659

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I trial of pazopanib in patients with advanced cancer.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first- and third-generation Japanese populations: comparison with Korean, Chinese, and Caucasian populations

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Diphenhydramine alters the disposition of venlafaxine through inhibition of CYP2D6 activity in humans

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: intraindividual variability and plasma concentration correlations

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

PhRMA white paper on ADME pharmacogenomics.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.158

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2010.158

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

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