(Q42918070)

English

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

scientific article published on 14 December 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018863%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018863%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Mohammad T Mazhab-Jafari

1

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15 January 2020

Christopher B Marshall

2

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15 January 2020

Matthew J. Smith

4

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15 January 2020

6

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15 January 2020

Robert Rottapel

7

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15 January 2020

Mitsuhiko Ikura

9

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15 January 2020

author name string

Geneviève M C Gasmi-Seabrook

5

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15 January 2020

Benjamin G Neel

8

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15 January 2020

Matthew Smith

3

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15 January 2020

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14 December 2009

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15 January 2020

number of pages

5

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Journal of Biological Chemistry

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15 January 2020

285

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15 January 2020

8

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15 January 2020

5132-5136

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15 January 2020

Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.

1 reference

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27 May 2018

Membrane-dependent signal integration by the Ras activator Son of sevenless

1 reference

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27 May 2018

Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577

1 reference

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27 May 2018

A Ras-induced conformational switch in the Ras activator Son of sevenless

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Fluorescence approaches for monitoring interactions of Rho GTPases with nucleotides, regulators, and effectors.

1 reference

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27 May 2018

Structural basis for the unique biological function of small GTPase RHEB

1 reference

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27 May 2018

The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle

1 reference

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27 May 2018

Structural analysis of autoinhibition in the Ras activator Son of sevenless

1 reference

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27 May 2018

GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes

1 reference

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27 May 2018

Preliminary crystallographic analysis of the complex of the human GTPase RhoA with the DH/PH tandem of PDZ-RhoGEF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Characterization of the interactions between the small GTPase RhoA and its guanine nucleotide exchange factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Fluorescent guanine nucleotide analogs and G protein activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Hydrolysis of GTP by p21NRAS, the NRAS protooncogene product, is accompanied by a conformational change in the wild-type protein: use of a single fluorescent probe at the catalytic site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

27 May 2018

Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

16 August 2018

Structure of a transient intermediate for GTP hydrolysis by ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

16 August 2018

Monitoring the real-time kinetics of the hydrolysis reaction of guanine nucleotide-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

16 August 2018

Structure of the G60A mutant of Ras: implications for the dominant negative effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820739

16 August 2018

Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate

1 reference

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16 August 2018

The mechanism of Ras GTPase activation by neurofibromin.

1 reference

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16 August 2018

Fluorescence methods in the study of small GTP-binding proteins

1 reference

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16 August 2018

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

1 reference

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21 January 2018

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018863

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018863

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018863

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of nucleotide release from Rho by the GDP dissociation stimulator protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018863

12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.C109.064766

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018863%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018863%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018863%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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