(Q42918132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Regulation of the tumour suppressor Fbw7α by PKC-dependent phosphorylation and cancer-associated mutations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Peter Joseph Jacques Parker

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Joanne Durgan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

432

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

77-87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10

13 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The Fbxw7/hCdc4 tumor suppressor in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Protein kinase C and other diacylglycerol effectors in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Protein kinase C epsilon: an oncogene and emerging tumor biomarker

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Protein kinase C iota: human oncogene, prognostic marker and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Protein kinase C: poised to signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Novel phosphorylation site markers of protein kinase C delta activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Involvement of epidermal growth factor-like domain of NELL proteins in the novel protein-protein interaction with protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Kinase peptide specificity: improved determination and relevance to protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Imaging protein kinase Calpha activation in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The landscape of somatic copy-number alteration across human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Fbw7/hCDC4 dimerization regulates its substrate interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Phosphorylation of nuclear localization signal inhibits the ligand-dependent nuclear import of aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Classical nuclear localization signals: definition, function, and interaction with importin alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100799

21 January 2018

Identifiers

DOI

10.1042/BJ20100799

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20815813%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference