(Q42933747)

11 November 2017

title

Synergistic inhibition of glycinergic transmission in vitro and in vivo by flavonoids and strychnine (English)

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11 November 2017

1

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11 November 2017

Ulrike Breitinger

2

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11 November 2017

Laila Mahran

series ordinal

3

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11 November 2017

Nahla Ayoub

series ordinal

4

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11 November 2017

Hans-Georg Breitinger

series ordinal

5

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11 November 2017

publication date

18 August 2010

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11 November 2017

published in

Toxicological Sciences

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11 November 2017

volume

118

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11 November 2017

issue

1

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11 November 2017

page(s)

171-182

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Glycine receptors: heterogeneous and widespread in the mammalian brain

11 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Structure, diversity and synaptic localization of inhibitory glycine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Fast kinetic analysis of ligand-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

The inhibitory glycine receptor-simple views of a complicated channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picrotoxin in glycine alpha 1 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Systems biology and combination therapy in the quest for clinical efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

On the mechanism of the gamma-aminobutyric acid receptor in the mammalian (mouse) cerebral cortex. Chemical kinetic investigations with a 10-ms time resolution adapted to measurements of neuronal receptor function in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Investigation of the alpha(1)-glycine receptor channel-opening kinetics in the submillisecond time domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Pharmacological studies on synthetic flavonoids: comparison with diazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Advances in flavonoid research since 1992.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

The biochemistry and medical significance of the flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

The effect of Ginkgo biloba (EGb 761) on epileptic activity in rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Cocaine and phencyclidine inhibition of the acetylcholine receptor: analysis of the mechanisms of action based on measurements of ion flux in the millisecond-to-minute time region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Cocaine, phencyclidine, and procaine inhibition of the acetylcholine receptor: characterization of the binding site by stopped-flow measurements of receptor-controlled ion flux in membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Human glycine alpha1 receptor inhibition by quercetin is abolished or inversed by alpha267 mutations in transmembrane domain 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Differential regulations of quercetin and its glycosides on ligand-gated ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

The glycinergic inhibitory synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

The protein tyrosine kinase inhibitor, genistein, decreases excitability of nociceptive neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Molecular structure and function of the glycine receptor chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Native glycine receptor subtypes and their physiological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Myricetin and quercetin, the flavonoid constituents of Ginkgo biloba extract, greatly reduce oxidative metabolism in both resting and Ca(2+)-loaded brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Effect of two flavonoid compounds on central nervous system. Analgesic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Anxiolytic natural and synthetic flavonoid ligands of the central benzodiazepine receptor have no effect on memory tasks in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Statistical analysis of drug combinations for synergism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Chemical kinetic measurements of a mammalian acetylcholine receptor by a fast-reaction technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ245

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFQ245

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11 November 2017

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