(Q42953208)

11 November 2017

Length matters: C-terminal tails regulate Mdm2-MdmX complexes (English)

1 reference

11 November 2017

Masha V Poyurovsky

1

1 reference

11 November 2017

1 April 2012

1 reference

11 November 2017

1 reference

11 November 2017

11

1 reference

11 November 2017

8

1 reference

11 November 2017

1485

1 reference

Mutational analysis of Mdm2 C-terminal tail suggests an evolutionarily conserved role of its length in Mdm2 activity toward p53 and indicates structural differences between Mdm2 homodimers and Mdm2/MdmX heterodimers

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3342954

Solution Structure of the Hdm2 C2H2C4 RING, a Domain Critical for Ubiquitination of p53

26 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.20047

21 January 2018

Identifiers

DOI

10.4161/CC.20047

1 reference

11 November 2017

1 reference

PMC publication ID

3342954

11 November 2017

PubMed publication ID

22544075

1 reference

PMC publication ID

3342954