(Q42970293)

11 November 2017

title

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy (English)

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11 November 2017

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10

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11 November 2017

M Sedeek

1

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11 November 2017

G Callera

2

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11 November 2017

A Montezano

3

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11 November 2017

A Gutsol

4

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11 November 2017

F Heitz

5

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11 November 2017

C Szyndralewiez

6

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11 November 2017

P Page

7

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11 November 2017

C R J Kennedy

8

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11 November 2017

K D Burns

9

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R L Hébert

11

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11 November 2017

publication date

14 July 2010

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American Journal of Physiology - Renal Physiology

11 November 2017

published in

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11 November 2017

volume

299

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11 November 2017

issue

6

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11 November 2017

page(s)

F1348-58

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Expression, localization, and function of the thioredoxin system in diabetic nephropathy

11 November 2017

cites work

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00028.2010

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Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid?

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NOX family NADPH oxidases: not just in mammals

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Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats

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Subcellular localization of Nox4 and regulation in diabetes

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New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy

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Mouse models of diabetic nephropathy

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Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src

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Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment

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Diabetic nephropathy: where hemodynamics meets metabolism

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Oxidative stress as a major culprit in kidney disease in diabetes

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Identification of renox, an NAD(P)H oxidase in kidney

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NADPH oxidases in the kidney

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Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells

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Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

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Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney

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Impact of genetic background on nephropathy in diabetic mice

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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

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Integrating albuminuria and GFR in the assessment of diabetic nephropathy

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Involvement of oxidative stress in the pathogenesis of diabetes

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Vascular NAD(P)H oxidases: specific features, expression, and regulation

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Effects of alpha-lipoic acid on transforming growth factor beta1-p38 mitogen-activated protein kinase-fibronectin pathway in diabetic nephropathy

21 January 2018

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

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The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction

21 January 2018

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Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma

21 January 2018

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Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components

21 January 2018

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End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions

21 January 2018

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Redox control of vascular smooth muscle migration

21 January 2018

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Transcription factors in the pathogenesis of diabetic nephropathy

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00028.2010

NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy

21 January 2018

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Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

21 January 2018

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Oxidants in chronic kidney disease

21 January 2018

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A novel superoxide-producing NAD(P)H oxidase in kidney

21 January 2018

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Diabetic nephropathy: important pathophysiologic mechanisms

21 January 2018

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Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR.

21 January 2018

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AGE, RAGE, and ROS in diabetic nephropathy.

21 January 2018

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Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway

21 January 2018

1 reference

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Suppressing renal NADPH oxidase to treat diabetic nephropathy

21 January 2018

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Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression

21 January 2018

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TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses

21 January 2018

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NAD(P)H oxidase-stimulating activity of serum from type 2 diabetic patients with retinopathy mediates enhanced endothelial expression of E-selectin

21 January 2018

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ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells.

21 January 2018

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10.1152/AJPRENAL.00028.2010

21 January 2018

Identifiers

DOI

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11 November 2017

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