(Q42977652)

English

Histone deacetylase inhibition activates transgene expression from integration-defective lentiviral vectors in dividing and non-dividing cells.

scientific article published on 11 December 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Histone deacetylase inhibition activates transgene expression from integration-defective lentiviral vectors in dividing and non-dividing cells (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Josephine M Janssen

2

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17 February 2020

Manuel A F V Gonçalves

3

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17 February 2020

author name string

Laetitia P L Pelascini

1

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17 February 2020

publication date

11 December 2012

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17 February 2020

Human Gene Therapy

1 reference

Europe PubMed Central

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17 February 2020

24

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17 February 2020

1

1 reference

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17 February 2020

78-96

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Combinatorial complexity in chromatin structure and function: revisiting the histone code

1 reference

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1 reference

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Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

1 reference

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1 reference

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Host cell detection of noncoding stuffer DNA contained in helper-dependent adenovirus vectors leads to epigenetic repression of transgene expression

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Integration-deficient lentiviral vectors: a slow coming of age.

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Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

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A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

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Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

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Combinatorial patterns of histone acetylations and methylations in the human genome

1 reference

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

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Use of nonintegrating lentiviral vectors for gene therapy

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High-resolution profiling of histone methylations in the human genome

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High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms

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Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1089/HUM.2012.069

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23140481%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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