(Q42983587)

English

Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives

scientific article published on September 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives (English)

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

author name string

H Grøn

1

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

I B Thøgersen

2

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

S V Pizzo

4

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

language of work or name

0 references

publication date

1 September 1996

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

number of pages

7

1 reference

based on heuristic

inferred from page(s)

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

318 ( Pt 2)

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

539-545

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Binding of platelet-derived growth factor-BB and transforming growth factor-beta 1 to alpha 2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized alpha 2-macroglobulin conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Identification of monomeric alpha-macroglobulin proteinase inhibitors in birds, reptiles, amphibians and mammals, and purification and characterization of a monomeric alpha-macroglobulin proteinase inhibitor from the American bullfrog Rana catesbeia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Receptor-mediated antigen delivery into macrophages. Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

The relationship between low density lipoprotein-related protein/alpha 2-macroglobulin (alpha 2M) receptors and the newly described alpha 2M signaling receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Invertebrate alpha 2-macroglobulin: structure-function and the ancient thiol ester bond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Thiol ester role in correct folding and conformation of human alpha 2-macroglobulin. Properties of recombinant C949S variant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Effect of methylamine and plasmin on the conformation of human alpha 2-macroglobulin as revealed by differential scanning calorimetric analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Relation of internal thioesters to conformational change and receptor-recognition site in α2-macroglobulin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Peptide models of protein metastable binding sites: competitive kinetics of isomerization and hydrolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Pregnancy zone protein, a proteinase-binding macroglobulin. Interactions with proteinases and methylamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Proteinase binding and inhibition by the monomeric alpha-macroglobulin rat alpha 1-inhibitor-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Cytokine binding and clearance properties of proteinase-activated alpha 2-macroglobulins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

An alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Heat-induced fragmentation of human alpha 2-macroglobulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Physical and chemical properties of human plasma β2-macroglobulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

26 May 2018

Evidence from sequence analysis that hen egg-white ovomacroglobulin (ovostatin) is devoid of an internal beta-Cys-gamma-Glu thiol ester

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

16 August 2018

Antibodies against viral proteins can be produced effectively in response to the increased uptake of alpha 2-macroglobulin:viral protein conjugate by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217654

16 August 2018

p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and physicochemical characterization of a new rat plasma proteinase inhibitor, alpha 1-inhibitor III

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional modifications of alpha 2-macroglobulin by primary amines. I. Characterization of alpha 2 M after derivatization by methylamine and by factor XIII

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An equilibrium model of the metastable binding sites of alpha 2-macroglobulin and complement proteins C3 and C4

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovostatin: a novel proteinase inhibitor from chicken egg white. I. Purification, physicochemical properties, and tissue distribution of ovostatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovostatin: a novel proteinase inhibitor from chicken egg white. II. Mechanism of inhibition studied with collagenase and thermolysin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic lactam and thiolactone models of protein metastable binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circular dichroic spectroscopy of non-human α-macroglobulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the binding of chicken α-macroglobulin and ovomacroglobulin to the mammalian α2-macroglobulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of thiolester bond cleavage-dependent conformational changes in binary alpha 2-macroglobulin-proteinase complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and initial characterization of an intermediate, half-cleaved form of human alpha 2-macroglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition and partial reversal of the methylamine-induced conversion of "slow" to "fast" electrophoretic forms of human alpha 2-macroglobulin by modification of the thiols

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous reformation of the intramolecular thioester in complement protein C3 and low temperature capture of a conformational intermediate capable of reformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous thioester bond formation in alpha 2-macroglobulin, C3 and C4

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the proteinase inhibition mechanism of human α2‐macroglobulin and pregnancy zone protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Macroglobulins: detection and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methanethiolation of the liberated cysteine residues of human alpha 2-macroglobulin treated with methylamine generates a derivative with similar functional characteristics as native alpha 2-macroglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bait region-thiol ester mapping in human alpha 2-macroglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational folding of alpha 1-inhibitor 3. Evidence for a compaction process

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiol ester cleavage-dependent conformational change in human alpha 2-macroglobulin. Influence of attacking nucleophile and of Cys949 modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The temperature-sensitive bond in human alpha 2-macroglobulin is the alkylamine-reactive site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8809044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3180539

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

ResearchGate publication ID

0 references

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