(Q42983982)

12 November 2017

title

A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy (English)

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12 November 2017

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4

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12 November 2017

Alexander A. Khromykh

10

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12 November 2017

D Hoang-Le

1

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12 November 2017

L Smeenk

2

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12 November 2017

I Anraku

3

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12 November 2017

X J Wang

5

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12 November 2017

J de Vrij

6

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12 November 2017

W J Liu

7

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12 November 2017

T T Le

8

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12 November 2017

W A Schroder

9

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12 November 2017

A Suhrbier

11

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12 November 2017

publication date

18 December 2008

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12 November 2017

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12 November 2017

volume

16

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12 November 2017

issue

2

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12 November 2017

page(s)

190-199

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

12 November 2017

cites work

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Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers

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Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications

21 January 2018

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Tetracycline-inducible packaging cell line for production of flavivirus replicon particles

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High fidelity of yellow fever virus RNA polymerase

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Stable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors

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Intratumoral immunotherapy: using the tumour against itself

21 January 2018

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Delivery of granulocyte-macrophage colony-stimulating factor in bioadhesive hydrogel stimulates migration of dendritic cells in models of human papillomavirus-associated (pre)neoplastic epithelial lesions

21 January 2018

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Trafficking of tumor peptide-specific cytotoxic T lymphocytes into the tumor microcirculation

21 January 2018

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In situ recruitment of antigen-presenting cells by intratumoral GM-CSF gene delivery

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Role of immature myeloid Gr-1+ cells in the development of antitumor immunity

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Administration of IFN-alpha enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell vaccine

21 January 2018

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Tumor regression induced by intratumor therapy with a disabled infectious single cycle (DISC) herpes simplex virus (HSV) vector, DISC/HSV/murine granulocyte-macrophage colony-stimulating factor, correlates with antigen-specific adaptive immunity.

21 January 2018

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New pharmacokinetic and pharmacodynamic tools for interferon-alpha (IFN-alpha) treatment of human cancer.

21 January 2018

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Type I interferons keep activated T cells alive

21 January 2018

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Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

21 January 2018

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

21 January 2018

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Sequential delivery of interferon-alpha gene and DCs to intracranial gliomas promotes an effective antitumor response

21 January 2018

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Characterization of Monocyte-Derived Dendritic Cells Maturated With IFN-alpha

21 January 2018

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Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription

21 January 2018

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A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

21 January 2018

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Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy

21 January 2018

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Temperature reduction in cultures of hGM-CSF-expressing CHO cells: effect on productivity and product quality

21 January 2018

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Preclinical evaluation of DISC-GMCSF for the treatment of breast carcinoma

21 January 2018

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Dendritic cell therapy with interferon-alpha synergistically suppresses outgrowth of established tumors in a murine colorectal cancer model

21 January 2018

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Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins

21 January 2018

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Kunjin replicon-based simian immunodeficiency virus gag vaccines

21 January 2018

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Evaluation of replicative capacity and genetic stability of West Nile virus replicons using highly efficient packaging cell lines

21 January 2018

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Genetic instability of vaccinia virus containing artificially duplicated genome regions

21 January 2018

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Novel design architecture for genetic stability of recombinant poliovirus: the manipulation of G/C contents and their distribution patterns increases the genetic stability of inserts in a poliovirus-based RPS-Vax vector system

21 January 2018

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Genetically stable picornavirus expression vectors with recombinant internal ribosomal entry sites

21 January 2018

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Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity

21 January 2018

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Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases

21 January 2018

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Infection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.169

Particle-mediated cytokine gene therapy leads to antitumor and antimetastatic effects in mouse carcinoma models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

Complete Regression of Established Subcutaneous B16 Murine Melanoma Tumors after Delivery of an HIV-1 Vpr-Expressing Plasmid by in Vivo Electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.169

Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.169

Kunjin virus replicon vaccine vectors induce protective CD8+ T-cell immunity

21 January 2018

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NS1 protein secretion during the acute phase of West Nile virus infection

21 January 2018

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The serine proteinase inhibitor (serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon alpha/beta priming

21 January 2018

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Cytotoxic T cell polyepitope vaccines delivered by ISCOMs

21 January 2018

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Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2008.169

In vivo electroporation of plasmids encoding GM-CSF or interleukin-2 into existing B16 melanomas combined with electrochemotherapy induces long-term antitumour immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Adenoviral-mediated interferon α overcomes resistance to the interferon protein in various cancer types and has marked bystander effects

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Immunostimulatory properties of human dendritic cells generated using IFN-beta associated either with IL-3 or GM-CSF

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Priming of naive T cells inside tumors leads to eradication of established tumors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Immunostimulating capacities of stabilized RNA molecules

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Dendritic cells differentiated in the presence of IFN-β and IL-3 are potent inducers of an antigen-specific CD8+ T cell response

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

IgE-mediated activation of NK cells through Fc gamma RIII

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.169

7 January 2021

Identifiers

DOI

10.1038/GT.2008.169

1 reference

Dimensions Publication ID

12 November 2017

1013936791

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1 reference