(Q43002766)

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Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes

scientific article published in April 2003

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scholarly article

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Europe PubMed Central

PMC publication ID

12 November 2017

Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes (English)

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

author name string

Anthony J Barron

1

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

Stephen G Finn

2

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Europe PubMed Central

PMC publication ID

12 November 2017

Stephen J Fuller

3

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

language of work or name

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publication date

1 April 2003

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Europe PubMed Central

PMC publication ID

12 November 2017

Biochemical Journal

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Europe PubMed Central

PMC publication ID

12 November 2017

371

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Europe PubMed Central

PMC publication ID

12 November 2017

Pt 1

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

71-79

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.

1 reference

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26 May 2018

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

1 reference

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26 May 2018

Activation of protein kinase cascades in the heart by hypertrophic G protein-coupled receptor agonists

1 reference

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26 May 2018

Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro

1 reference

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26 May 2018

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

1 reference

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26 May 2018

Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases

1 reference

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26 May 2018

Signaling in myocardial hypertrophy: life after calcineurin?

1 reference

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26 May 2018

The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation

1 reference

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26 May 2018

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Stimulation of gene expression in neonatal rat ventricular myocytes by Ras is mediated by Ral guanine nucleotide dissociation stimulator (Ral.GDS) and phosphatidylinositol 3-kinase in addition to Raf.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Signaling pathways in cardiac myocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Stimulation of phosphatidylinositol hydrolysis, protein kinase C translocation, and mitogen-activated protein kinase activity by bradykinin in rat ventricular myocytes: dissociation from the hypertrophic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

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26 May 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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26 May 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Activation of Ras and Other Signaling Pathways by Receptor Tyrosine Kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

1 reference

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26 May 2018

Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein g

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

26 May 2018

Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

Role of reactive oxygen species in IL-1 beta-stimulated sustained ERK activation and MMP-9 induction

1 reference

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16 August 2018

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

16 August 2018

Extracellular Signal-regulated Kinase Plays an Essential Role in Hypertrophic Agonists, Endothelin-1 and Phenylephrine-induced Cardiomyocyte Hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223261

1 December 2018

Differential Regulation of Parallel Mitogen-Activated Protein Kinases in Cardiac Myocytes Revealed by Phosphatase Inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of macrophage migration inhibitory factor to extracellular signal-regulated kinase activation by oxidative stress in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal g

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12513686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20021395

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

ResearchGate publication ID

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