(Q43035653)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451504%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691) (English)

1 reference

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27 January 2020

0 references

14

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27 January 2020

author name string

M D Fidock

1

1 reference

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27 January 2020

B E Souberbielle

2

1 reference

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27 January 2020

C Laxton

3

1 reference

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27 January 2020

J Rawal

4

1 reference

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27 January 2020

O Delpuech-Adams

5

1 reference

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27 January 2020

T P Corey

6

1 reference

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27 January 2020

P Colman

7

1 reference

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27 January 2020

V Kumar

8

1 reference

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27 January 2020

J B Cheng

9

1 reference

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27 January 2020

K Wright

10

1 reference

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27 January 2020

S Srinivasan

11

1 reference

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27 January 2020

K Rana

12

1 reference

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27 January 2020

C Craig

13

1 reference

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27 January 2020

M Perros

15

1 reference

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27 January 2020

M Westby

16

1 reference

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27 January 2020

R Webster

17

1 reference

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27 January 2020

E van der Ryst

18

1 reference

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27 January 2020

language of work or name

English

0 references

publication date

30 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451504%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

27 January 2020

published in

1 reference

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27 January 2020

volume

89

1 reference

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27 January 2020

issue

6

1 reference

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27 January 2020

page(s)

821-829

1 reference

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The global burden of hepatitis C

27 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Immune response modifiers--mode of action

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Investigating Toll-Like Receptor Agonists for Potential To Treat Hepatitis C Virus Infection

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

The pharmacology of endosomal TLR agonists in viral disease

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Pharmacokinetics of 852A, an imidazoquinoline Toll-like receptor 7-specific agonist, following intravenous, subcutaneous, and oral administrations in humans

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

An exploratory study of systemic administration of the toll-like receptor-7 agonist 852A in patients with refractory metastatic melanoma

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Sensitization to TLR7 agonist in IFN-beta-preactivated dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Loxoribine, a selective Toll-like receptor 7 agonist, induces maturation of human monocyte-derived dendritic cells and stimulates their Th-1- and Th-17-polarizing capability.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Exhaustive genotyping of the interferon alpha receptor 1 (IFNAR1) gene and association of an IFNAR1 protein variant with AIDS progression or susceptibility to HIV-1 infection in a French AIDS cohort.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Regulation of gene expression by pegylated IFN-alpha2b and IFN-alpha2b in human peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Ido brings down the pressure in systemic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Managing premedications and the risk for reactions to infusional monoclonal antibody therapy

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Vaccine immunopotentiators of the future

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.60

7 January 2021

Identifiers

DOI

10.1038/CLPT.2011.60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21451504%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference