(Q43050485)

English

Cytotoxicity of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) on Mer+, Mer+Rem- and Mer- cell lines: differential potentiation by 3-acetamidobenzamide

scientific article published in January 1988

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

13 November 2017

Cytotoxicity of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) on Mer+, Mer+Rem- and Mer- cell lines: differential potentiation by 3-acetamidobenzamide (English)

1 reference

Europe PubMed Central

13 November 2017

5-(3-methyl-1-triazeno)imidazole-4-carboxamide

1 reference

ChEBI release 2020-05-28

author name string

Lunn JM

1

1 reference

Europe PubMed Central

13 November 2017

Harris AL

2

1 reference

Europe PubMed Central

13 November 2017

language of work or name

0 references

publication date

1 January 1988

1 reference

Europe PubMed Central

13 November 2017

British Journal of Cancer

1 reference

Europe PubMed Central

13 November 2017

57

1 reference

Europe PubMed Central

13 November 2017

1

1 reference

Europe PubMed Central

13 November 2017

54-58

1 reference

Europe PubMed Central

13 November 2017

https://scigraph.springernature.com/pub.10.1038/bjc.1988.8

0 references

DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Extracts of chronic lymphocytic leukemia lymphocytes have a high level of DNA repair activity fo O6-methylguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

A simplified assay for O6-methylguanine-DNA methyltransferase activity and its application to human neoplastic and non-neoplastic tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Sensitivity of human cell strains having different abilities to repair O6-methylguanine in DNA to inactivation by alkylating agents including chloroethylnitrosoureas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Regulation of DNA ligase activity by poly(ADP-ribose)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Novel inhibitors of poly(ADP-ribose) synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Mechanism of carcinogenesis with 1-aryl-3,3-dialkyltriazenes. II. In vitro-alkylation of guanosine, RNA and DNA with aryl-monoalkyltriazenes to form 7-alkylguanine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

The cytotoxic and mutagenic effects of alkylating agents on human lymphoid cells are caused by different DNA lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Differential cytotoxicity and DNA-damaging effects produced in human cells of the Mer+ and Mer- phenotypes by a series of alkyltriazenylimidazoles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Poly(ADP-ribose) synthesis is involved in the toxic effects of alkylating agents but does not regulate DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Repair of DNA O-alkylation damage by various human organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Antitumour imidazotetrazines--XI: Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one [CCRG 81045; M and B 39831 NSC 362856] on poly(ADP-ribose) metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

In vivo metabolism and reaction with DNA of the cytostatic agent, 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Role of DTIC (NSC-45388) in the chemotherapy of sarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

DTIC (NSC-45388) in malignant melanoma: a perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

The Involvement of Poly(ADP-ribose) Polymerase in the Degradation of NAD Caused by gamma-Radiation and N-Methyl-N-Nitrosourea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

26 May 2018

Properties of human melanoma cells resistant to 5-(3',3'-dimethyl-1-triazeno)imidazole-4-carboxamide and other methylating agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

16 August 2018

Tumor inhibitory triazenes. 3. Dealkylation within an homologous series and its relation to antitumor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

16 August 2018

O6-alkylguanine-DNA alkyltransferase activity in normal human tissues and cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

16 August 2018

Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

16 August 2018

3-Aminobenzamide does not increase repair patch size in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2246699

16 August 2018

Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly ADP-ribosylation--a cellular emergency reaction?

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of poly(ADP-ribose)polymerase causes increased DNA strand breaks without decreasing strand rejoining in alkylated HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA strand breaks, NAD metabolism, and programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

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based on heuristic

inferred from PubMed ID database lookup

A simple ultramicro method for determination of pyridine nucleotides in tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(ADP-ribose)n participates in DNA excision repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O6-Methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase inhibitors preserve oxidized nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

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based on heuristic

inferred from PubMed ID database lookup

O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic repair of premutagenic DNA lesions in human epidermis. Quantitation of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/2831926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.1988.8

1 reference

Europe PubMed Central

13 November 2017

1 reference

Europe PubMed Central

13 November 2017

1 reference

Europe PubMed Central

13 November 2017

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