(Q43056852)

13 November 2017

Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila (English)

1 reference

Insulin degrading metalloproteinase Dmel_CG5517

13 November 2017

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GOA release 2020-03-11

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1 reference

3

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13 November 2017

Manabu Tsuda

1

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13 November 2017

Toshikazu Kobayashi

series ordinal

2

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13 November 2017

Toshiro Aigaki

series ordinal

4

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13 November 2017

language of work or name

English

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publication date

21 May 2010

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13 November 2017

5

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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13 November 2017

584

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13 November 2017

13

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13 November 2017

2916-2920

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Insulin signalling and the regulation of glucose and lipid metabolism

13 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Diet, nutrition and the prevention of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

The risk of dementia among persons with diabetes mellitus: a population-based cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Genetic Transformation of Drosophila with Transposable Element Vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Ends-out, or replacement, gene targeting in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

The calcineurin regulator sra plays an essential role in female meiosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.010

10.1016/J.FEBSLET.2010.05.010

21 January 2018

Identifiers

DOI

1 reference

13 November 2017

1 reference