(Q43057681)

13 November 2017

Zinc, zinc transporters and diabetes (English)

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13 November 2017

J Rungby

1

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13 November 2017

21 May 2010

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13 November 2017

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13 November 2017

53

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13 November 2017

8

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13 November 2017

1549-1551

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https://scigraph.springernature.com/pub.10.1007/s00125-010-1793-x

13 November 2017

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cites work

Insulinomimetic bis(maltolato)zinc(II) complex: blood glucose normalizing effect in KK-A(y) mice with type 2 diabetes mellitus.

1 reference

12 December 2020

Clioquinol attenuates zinc-dependent beta-cell death and the onset of insulitis and hyperglycemia associated with experimental type I diabetes in mice

1 reference

12 December 2020

Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation

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12 December 2020

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

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12 December 2020

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

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12 December 2020

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release

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12 December 2020

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

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12 December 2020

Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function

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12 December 2020

Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency

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12 December 2020

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12 December 2020

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

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12 December 2020

Effect of Zinc Deficiency in Rats on Insulin Release from the Pancreas

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12 December 2020

Abnormal zinc metabolism in type II diabetes mellitus

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12 December 2020

Zinc and diabetes--clinical links and molecular mechanisms

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12 December 2020

Hyperzincuria in insulin treated diabetes mellitus—its relation to glucose homeostasis and insulin administration

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12 December 2020

Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes

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12 December 2020

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

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12 December 2020

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

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12 December 2020

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

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12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

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12 December 2020

Think zinc: New roles for zinc in the control of insulin secretion

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12 December 2020

SLC30A8 polymorphism and type 2 diabetes risk: evidence from 27 study groups

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12 December 2020

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

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12 December 2020

SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.

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12 December 2020

Zinc as a paracrine effector in pancreatic islet cell death

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12 December 2020

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

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12 December 2020

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

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12 December 2020

ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation

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12 December 2020

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

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12 December 2020

The Zn2+-transporting pathways in pancreatic beta-cells: a role for the L-type voltage-gated Ca2+ channel

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12 December 2020

Zinc-transporter genes in human visceral and subcutaneous adipocytes: lean versus obese

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12 December 2020

10.1007/S00125-010-1793-X

Identifiers

DOI

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13 November 2017

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PubMed ID

20490449