(Q43093699)

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Testosterone modulates gene expression pathways regulating nutrient accumulation, glucose metabolism and protein turnover in mouse skeletal muscle.

scientific article published in February 2011

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31 January 2020

Testosterone modulates gene expression pathways regulating nutrient accumulation, glucose metabolism and protein turnover in mouse skeletal muscle (English)

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31 January 2020

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Matthew T. Haren

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31 January 2020

author name string

A M Siddiqui

2

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31 January 2020

H J Armbrecht

3

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31 January 2020

R T Kevorkian

4

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31 January 2020

M J Kim

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M J Haas

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31 January 2020

A Mazza

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31 January 2020

Vijaya B Kumar

8

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31 January 2020

M Green

9

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31 January 2020

W A Banks

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31 January 2020

J E Morley

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publication date

1 February 2011

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31 January 2020

International Journal of Andrology

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31 January 2020

1

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55-68

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31 January 2020

The ABCs of IGF-I isoforms: impact on muscle hypertrophy and implications for repair

1 reference

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21 January 2018

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men.

1 reference

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Predictors of skeletal muscle mass in elderly men and women.

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21 January 2018

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

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Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

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PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance

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IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines despite activation of Akt/Foxo and GSK-3beta pathways and inhibition of atrogin-1 mRNA.

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Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting

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Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle.

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Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion.

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21 January 2018

Testosterone administration to older men improves muscle function: molecular and physiological mechanisms

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21 January 2018

Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of {beta}-catenin

1 reference

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21 January 2018

The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men.

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21 January 2018

A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression.

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Identifying biological themes within lists of genes with EASE

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DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists

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Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin

1 reference

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21 January 2018

Insulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cells

1 reference

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Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis.

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21 January 2018

Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels

1 reference

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21 January 2018

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism

1 reference

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21 January 2018

Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men.

1 reference

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21 January 2018

Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.

1 reference

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21 January 2018

Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid

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21 January 2018

Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

1 reference

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21 January 2018

Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor

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21 January 2018

Mechanisms of hemorrhage-induced hepatic insulin resistance: role of tumor necrosis factor-alpha

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Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element.

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21 January 2018

Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss

1 reference

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21 January 2018

Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.

1 reference

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Gene expression profiling of mice with genetically modified muscle glycogen content

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21 January 2018

Using ANOVA for gene selection from microarray studies of the nervous system

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Lipin, a lipodystrophy and obesity gene

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Aging, androgens, and the metabolic syndrome in a longitudinal study of aging

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Late onset of obesity in male androgen receptor-deficient (AR KO) mice

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Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways

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21 January 2018

Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life

1 reference

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21 January 2018

Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study

1 reference

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Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia

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Lipin deficiency impairs diurnal metabolic fuel switching.

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Identifiers

10.1111/J.1365-2605.2010.01061.X

1 reference

Europe PubMed Central

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31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20403060%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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