(Q43099250)

English

Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement.

scientific article published in April 2010

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31 January 2020

Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement (English)

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31 January 2020

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Cristiano Chiamulera

11

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31 January 2020

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31 January 2020

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Cecilia Gotti

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31 January 2020

Stefania Guiducci

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31 January 2020

Vincenzo Tedesco

3

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31 January 2020

Silvia Corbioli

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31 January 2020

Lara Zanetti

5

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31 January 2020

Milena Moretti

6

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31 January 2020

Alessio Zanardi

7

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31 January 2020

Roberto Rimondini

8

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31 January 2020

Manolo Mugnaini

9

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31 January 2020

Francesco Clementi

10

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31 January 2020

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publication date

1 April 2010

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31 January 2020

Journal of Neuroscience

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31 January 2020

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31 January 2020

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31 January 2020

5311-5325

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31 January 2020

Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of dopamine in the behavioural actions of nicotine related to addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic receptors at the amino acid level

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the alpha3 subunit in central nicotinic binding populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain reward circuitry: insights from unsensed incentives

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The motivational valence of nicotine in the rat ventral tegmental area is switched from rewarding to aversive following blockade of the alpha7-subunit-containing nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SSR591813, a novel selective and partial alpha4beta2 nicotinic receptor agonist with potential as an aid to smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of probe and tissue factors that influence interpretation of quantitative microdialysis experiments for dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of nigrostriatal alpha 6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by beta 3 subunit gene deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype alpha3beta2(al

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective down-regulation of [(125)I]Y0-alpha-conotoxin MII binding in rat mesostriatal dopamine pathway following continuous infusion of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain nicotinic acetylcholine receptors: native subtypes and their relevance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of nicotinic antagonists perfused into the nucleus accumbens or the ventral tegmental area on cocaine-induced dopamine release in the nucleus accumbens of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential nicotinic regulation of the nigrostriatal and mesolimbic dopaminergic pathways: implications for drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of alpha-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational research in medication development for nicotine dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrolytic lesions of the habenula attenuate brain stimulation reward.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure to nicotine and sensitization of nicotine-induced behaviors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal nicotinic acetylcholine receptors alpha 4* and alpha 6* differentially modulate dopamine release in mouse striatal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of multiple nicotinic acetylcholine receptors in the rat optic nerve: high densities of receptors containing alpha6 and beta3 subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term nicotine treatment differentially regulates striatal alpha6alpha4beta2* and alpha6(nonalpha4)beta2* nAChR expression and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propranolol transiently inhibits reinstatement of nicotine-seeking behaviour in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional diversity of native brain neuronal nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential central distribution of optic nerve components in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]nisoxetine--a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine subunit mRNA expression in dopaminergic neurons of the rat substantia nigra and ventral tegmental area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20392953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5095-09.2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20392953%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20392953%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20392953%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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