(Q43121719)

English

A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa.

scientific article published on 6 April 2009

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349426%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa (English)

1 reference

Europe PubMed Central

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25 January 2020

Pseudomonas aeruginosa

1 reference

based on heuristic

inferred from title

1

1 reference

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25 January 2020

author name string

Haiping Lu

2

1 reference

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25 January 2020

Nancy D Kock

3

1 reference

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25 January 2020

Daniel J Wozniak

4

1 reference

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25 January 2020

Steven B Mizel

5

1 reference

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25 January 2020

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publication date

6 April 2009

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25 January 2020

Infection and Immunity

1 reference

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25 January 2020

77

1 reference

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25 January 2020

6

1 reference

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25 January 2020

2356-2366

1 reference

Europe PubMed Central

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25 January 2020

Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates

1 reference

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25 May 2018

Mucosal adjuvant activity of flagellin in aged mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Protective immunity to pseudomonas aeruginosa induced with a capsid-modified adenovirus expressing P. aeruginosa OprF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

A double-blind randomized placebo-controlled phase III study of a Pseudomonas aeruginosa flagella vaccine in cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity

1 reference

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25 May 2018

Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The alternative sigma factor AlgT represses Pseudomonas aeruginosa flagellum biosynthesis by inhibiting expression of fleQ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Cellular mechanisms of the adjuvant activity of the flagellin component FljB of Salmonella enterica Serovar Typhimurium to potentiate mucosal and systemic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Infection and inflammation in cystic fibrosis: a short review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Pathogen-host interactions in Pseudomonas aeruginosa pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Mucosal administration of flagellin induces innate immunity in the mouse lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Flagellin fusion proteins as adjuvants or vaccines induce specific immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Murine complement interactions with Pseudomonas aeruginosa and their consequences during pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Role of Toll-like receptors in costimulating cytotoxic T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Type IV pili are not specifically required for contact dependent translocation of exoenzymes by Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Early infection and progression of cystic fibrosis lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The role of inflammation in the pathophysiology of CF lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Proteome analysis of the effect of mucoid conversion on global protein expression in Pseudomonas aeruginosa strain PAO1 shows induction of the disulfide bond isomerase, dsbA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Mouse models of chronic lung infection with Pseudomonas aeruginosa: models for the study of cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Induction of cytokine synthesis by flagella from gram-negative bacteria may be dependent on the activation or differentiation state of human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Intranasal administration of synthetic recombinant peptide-based vaccine protects mice from infection by Schistosoma mansoni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Gene replacement in Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Protection of immunocompromised mice against lethal infection with Pseudomonas aeruginosa by active or passive immunization with recombinant P. aeruginosa outer membrane protein F and outer membrane protein I fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Clearance of Pseudomonas aeruginosa from the murine gastrointestinal tract is effectively mediated by O-antigen-specific circulating antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The measurement of relative antibody affinity by ELISA using thiocyanate elution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Characterization of the susceptibility of Pseudomonas aeruginosa to complement-mediated killing: role of antibodies to the rough lipopolysaccharide on serum-sensitive strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The contribution of exoproducts to virulence of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Protection against experimental Pseudomonas aeruginosa infection by recombinant P. aeruginosa lipoprotein I expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Evaluation of protective mAbs against Pseudomonas aeruginosa outer membrane protein I by C1q binding assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

IgG subclass antibody responses to alginate from Pseudomonas aeruginosa in patients with cystic fibrosis and chronic P. aeruginosa infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Synthetic recombinant vaccine expressing influenza haemagglutinin epitope in Salmonella flagellin leads to partial protection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

The effect of complement depletion on lung clearance of bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

25 May 2018

Design of a liposomal candidate vaccine against Pseudomonas aeruginosa and its evaluation in triggering systemic and lung mucosal immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Differential cytokine profile in children with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Mucosal immunization with purified flagellin from Salmonella induces systemic and mucosal immune responses in C3H/HeJ mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Clinical study to assess the immunogenicity and safety of a recombinant Pseudomonas aeruginosa OprF-OprI vaccine in burn patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

15 August 2018

Bacterial flagellin is an effective adjuvant for CD4+ T cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687341

3 November 2018

Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: immunization using divalent flagella preparations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IgG subclass antibodies to Pseudomonas aeruginosa in sera from patients with chronic Ps. aeruginosa infection investigated by ELISA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-sectional and longitudinal studies of naturally occurring antibodies to Pseudomonas aeruginosa in cystic fibrosis indicate absence of antibody-mediated protection and decline in opsonic quality after infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing by overlap extension by PCR using asymmetric amplification: an improved technique for the generation of hybrid proteins of immunological interest

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of chronic bronchopulmonary Pseudomonas aeruginosa infection in resistant and susceptible inbred mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A recombinant hybrid outer membrane protein for vaccination against Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking of the TLR5 activation domain hampers protective potential of flagellin DNA vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a role for influenza vaccination in cystic fibrosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 typeNote

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenic efficacy of differently produced recombinant vaccines candidates against Pseudomonas aeruginosa infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased prevalence of mutations in the cystic fibrosis transmembrane conductance regulator in children with chronic rhinosinusitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19349426

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.00054-09

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349426%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349426%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349426%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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