(Q43138216)

14 November 2017

title

The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus (English)

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14 November 2017

3

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14 November 2017

4

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14 November 2017

Tero Viitanen

1

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14 November 2017

Eva Ruusuvuori

series ordinal

2

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14 November 2017

language of work or name

English

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publication date

8 March 2010

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14 November 2017

published in

Journal of Physiology

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14 November 2017

volume

588

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14 November 2017

issue

Pt 9

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14 November 2017

page(s)

1527-1540

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Cation-chloride cotransporters and neuronal function

14 November 2017

cites work

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Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference

30 September 2018

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GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1.

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Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory.

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30 September 2018

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Application of the physical disector to the central nervous system: estimation of the total number of neurons in subdivisions of the rat hippocampus.

30 September 2018

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30 September 2018

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30 September 2018

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Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII

30 September 2018

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A potential role for astrocytes in mediating the antiepileptic actions of furosemide in vitro.

30 September 2018

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GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex

30 September 2018

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Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2.

30 September 2018

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Carbonic anhydrase isoform VII acts as a molecular switch in the development of synchronous gamma-frequency firing of hippocampal CA1 pyramidal cells.

30 September 2018

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Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold

30 September 2018

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Mesial temporal lobe epilepsy: A pathological replay of developmental mechanisms?

30 September 2018

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Regulation and Modulation of pH in the Brain

30 September 2018

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30 September 2018

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Furosemide terminates limbic status epilepticus in freely moving rats

30 September 2018

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Cation-chloride co-transporters in neuronal communication, development and trauma

30 September 2018

1 reference

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BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

30 September 2018

1 reference

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Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro.

30 September 2018

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On the origin of interictal activity in human temporal lobe epilepsy in vitro.

30 September 2018

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Neonatal development of the rat visual cortex: synaptic function of GABAA receptor alpha subunits

30 September 2018

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Furosemide reveals heterogeneous GABA(A) receptor expression at adult rat Golgi cell to granule cell synapses.

30 September 2018

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Excitatory actions of gaba during development: the nature of the nurture

30 September 2018

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Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy

30 September 2018

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Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

30 September 2018

1 reference

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Enhanced temporal stability of cholinergic hippocampal gamma oscillations following respiratory alkalosis in vitro.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

GABAergic excitation and K(+)-mediated volume transmission in the hippocampus.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Pharmacological isolation of the synaptic and nonsynaptic components of the GABA-mediated biphasic response in rat CA1 hippocampal pyramidal cells.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Anticonvulsant actions of furosemide in vitro.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

A furosemide-sensitive K+-Cl- cotransporter counteracts intracellular Cl- accumulation and depletion in cultured rat midbrain neurons.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]o regulation

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Ionic mechanisms of spontaneous GABAergic events in rat hippocampal slices exposed to 4-aminopyridine.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Long-lasting GABA-mediated depolarization evoked by high-frequency stimulation in pyramidal neurons of rat hippocampal slice is attributable to a network-driven, bicarbonate-dependent K+ transient.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Alteration of GABAA receptor function following gene transfer of the CLC-2 chloride channel

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Developmental changes of inhibitory synaptic currents in cerebellar granule neurons: role of GABA(A) receptor alpha 6 subunit

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Interstitial PCO2 and pH in rat hippocampal slices measured by means of a novel fast CO2/H(+)-sensitive microelectrode based on a PVC-gelled membrane.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Role of HCO3- ions in depolarizing GABAA receptor-mediated responses in pyramidal cells of rat hippocampus.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Excitatory effects and electroencephalographic correlation of etomidate, thiopental, methohexital, and propofol

30 September 2018

1 reference

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Selective antagonist for the cerebellar granule cell-specific gamma-aminobutyric acid type A receptor

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Ionic basis of GABAA receptor channel function in the nervous system

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Cellular factors influencing GABA response in hippocampal pyramidal cells.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Transient changes in the size of the extracellular space in the sensorimotor cortex of cats in relation to stimulus-induced changes in potassium concentration

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Potassium accumulation in interstitial space during epileptiform seizures

30 September 2018

1 reference

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Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. II. Role of extracellular potassium.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Postsynaptic fall in intracellular pH induced by GABA-activated bicarbonate conductance.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Relative contributions of passive equilibrium and active transport to the distribution of chloride in mammalian cortical neurons

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Activity-dependent disinhibition. II. Effects of extracellular potassium, furosemide, and membrane potential on ECl- in hippocampal CA3 neurons.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Activity-dependent disinhibition. I. Repetitive stimulation reduces IPSP driving force and conductance in the hippocampus in vitro.

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones

30 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876807

Changes in extracellular K+ evoked by GABA, THIP and baclofen in the guinea-pig hippocampal slice

30 September 2018

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Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

30 September 2018

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Dissociation of Synchronization and Excitability in Furosemide Blockade of Epileptiform Activity

30 September 2018

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Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.181826

Reporting ethical matters in the Journal of Physiology: standards and advice

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.181826

Swelling and potassium uptake in cultured astrocytes

21 January 2018

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12 December 2020

Influence of GABA-gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres

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12 December 2020

Chloride-cotransport blockade desynchronizes neuronal discharge in the "epileptic" hippocampal slice

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12 December 2020

Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors

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12 December 2020

10.1113/JPHYSIOL.2009.181826

Identifiers

DOI

1 reference

14 November 2017

0 references

1 reference