(Q43141698)

English

Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 express

scientific article published on 13 February 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19218529%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19218529%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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1 reference

based on heuristic

inferred from title

mesenchymal stem cell

1 reference

based on heuristic

inferred from title

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19218529%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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Sheik Wisel

1

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21 January 2020

M Lakshmi Kuppusamy

3

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21 January 2020

I Krishna Mohan

4

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21 January 2020

Simi M Chacko

5

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21 January 2020

Brian K Rivera

6

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21 January 2020

Benjamin C Sun

7

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21 January 2020

Kálmán Hideg

8

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21 January 2020

Periannan Kuppusamy

9

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21 January 2020

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13 February 2009

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21 January 2020

Journal of Pharmacology and Experimental Therapeutics

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21 January 2020

329

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21 January 2020

2

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21 January 2020

543-550

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Europe PubMed Central

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21 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2672865/fullTextXML

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inferred from PubMed Central ID database lookup

Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction

1 reference

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25 May 2018

Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation

1 reference

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25 May 2018

Current status and future prospects for cell transplantation to prevent congestive heart failure

1 reference

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25 May 2018

Mesenchymal stem cells and cardiac repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Differentiation of osteoblasts and osteocytes from mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Cell-based therapy of myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Effects of trimetazidine on myocardial preconditioning in anesthetized rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels.

1 reference

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25 May 2018

Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice

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25 May 2018

Mesenchymal stem cells differentiate into an endothelial phenotype, reduce neointimal formation, and enhance endothelial function in a rat vein grafting model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Hypoxic preconditioning attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Trimetazidine protective effect against ischemia-induced susceptibility to ventricular fibrillation in pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function.

1 reference

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15 August 2018

Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Attenuation of myocardial ischemia-reperfusion injury by trimetazidine derivatives functionalized with antioxidant properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

15 August 2018

Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts.

1 reference

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15 August 2018

Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury

1 reference

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15 August 2018

The anti-anginal drug trimetazidine reduces neutrophil-mediated cardiac reperfusion injury

1 reference

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Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue.

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15 August 2018

Trimetazidine protects isolated rat hearts against ischemia-reperfusion injury in an experimental timing-dependent manner.

1 reference

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15 August 2018

Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia

1 reference

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Measurement of oxygen consumption in mouse aortic endothelial cells using a microparticulate oximetry probe

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Preconditioning and metabolic anti-ischaemic agents

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15 August 2018

Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase

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Bcl-2 Engineered MSCs Inhibited Apoptosis and Improved Heart Function

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Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart

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Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

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Direct measurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine

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Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation

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Effect of trimetazidine on mitochondrial function and oxidative damage during reperfusion of ischemic hypertrophied rat myocardium

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Structure-activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia-reperfusion injury

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Effects of chronic trimetazidine treatment on myocardial preconditioning in anesthetized rats

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Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium

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Identifiers

10.1124/JPET.109.150839

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Europe PubMed Central

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21 January 2020

release_37mwmfjkxbbbdpuafr76zdgkku

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24 November 2022

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21 January 2020

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Europe PubMed Central

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21 January 2020

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