(Q43167315)

15 November 2017

title

Dissociated non-steroidal glucocorticoids: tuning out untoward effects (English)

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15 November 2017

Michael L Mohler

1

1 reference

15 November 2017

Yali He

2

1 reference

15 November 2017

Zhongzhi Wu

3

1 reference

15 November 2017

Seoung-Soo Hong

4

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15 November 2017

Duane D Miller

5

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15 November 2017

language of work or name

English

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publication date

1 January 2007

1 reference

Expert Opinion on Therapeutic Patents

15 November 2017

published in

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15 November 2017

volume

17

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15 November 2017

issue

1

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15 November 2017

page(s)

37-58

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Troglitazone antagonizes metabolic effects of glucocorticoids in humans: effects on glucose tolerance, insulin sensitivity, suppression of free fatty acids, and leptin.

15 November 2017

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Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes

21 January 2018

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Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

21 January 2018

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Identification by microarray analysis of aspartate aminotransferase and glutamine synthetase as glucocorticoid target genes in a mouse Schwann cell line

21 January 2018

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DNA binding of the glucocorticoid receptor is not essential for survival

21 January 2018

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The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

21 January 2018

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Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis

21 January 2018

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Glucocorticoid-induced modulation of cytokine secretion from normal and leukemic human myelomonocytic cells.

21 January 2018

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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

21 January 2018

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Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an "agreement docking" method

21 January 2018

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Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series

21 January 2018

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Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

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Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand

21 January 2018

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Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

21 January 2018

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Substituted pyrazolo corticoids as topical antiinflammatory agents

21 January 2018

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Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy

21 January 2018

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Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity

21 January 2018

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Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity

21 January 2018

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Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

21 January 2018

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A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

21 January 2018

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Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

21 January 2018

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Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

21 January 2018

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Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature

21 January 2018

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Regulation of gene expression by PRA-910, a novel progesterone receptor modulator, in T47D cells

21 January 2018

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Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone.

21 January 2018

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Fast nongenomic effects of steroids on synaptic transmission and role of endogenous neurosteroids in spinal pain pathways

21 January 2018

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Steering estrogen signals from the plasma membrane to the nucleus: two sides of the coin

21 January 2018

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21 January 2018

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Glucocorticoid Ligands Specify Different Interactions with NF-κB by Allosteric Effects on the Glucocorticoid Receptor DNA Binding Domain

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1517/13543776.17.1.37

1 reference

15 November 2017

1 reference